MIT License

Copyright (c) 2026 Eagan

Permission is hereby granted, free of charge, to any person obtaining a copy
of this software and associated documentation files (the "Software"), to deal
in the Software without restriction, including without limitation the rights
to use, copy, modify, merge, publish, distribute, sublicense, and/or sell
copies of the Software, and to permit persons to whom the Software is
furnished to do so, subject to the following conditions:

The above copyright notice and this permission notice shall be included in all
copies or substantial portions of the Software.

THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE
AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM,
OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE
SOFTWARE.

Third-party data

The ecbackoff code is licensed under MIT above. The bundled reference and
example sequences are subsets of UniProtKB/Swiss-Prot from the UniProt
Consortium (https://www.uniprot.org/uniprot). The reference sequences were
selected from release 2026_04. The reference table combines selected
UniProtKB/Swiss-Prot annotations with data from the ENZYME nomenclature
database, maintained by the Swiss-Prot group at the SIB Swiss Institute
of Bioinformatics (https://enzyme.expasy.org/). The sequences and
annotations were selected and reformatted for ecbackoff.

UniProtKB/Swiss-Prot and the ENZYME database are licensed under the
Creative Commons Attribution 4.0 International license
(https://creativecommons.org/licenses/by/4.0/).

LicenseRef-IUBMB-ExplorEnz

The orphan table (data/orphan.tsv.gz) includes selected EC identifiers,
creation years and accepted names from ExplorEnz, the International Union
of Biochemistry and Molecular Biology (IUBMB) Enzyme Nomenclature database
(https://enzyme-database.org/). ExplorEnz entries are copyright 2001-2026
IUBMB. The database authors permit use in other applications with
acknowledgement of the source. See the Availability section of McDonald,
Boyce and Tipton, Nucleic Acids Research 37, D593-D597 (2009),
https://doi.org/10.1093/nar/gkn582. ecbackoff selects, reformats and ranks
a subset of these records.

Reaction similarity values in the orphan table are calculated from the
Rhea reaction knowledgebase (https://www.rhea-db.org/), available under
CC BY 4.0 (https://creativecommons.org/licenses/by/4.0/).
See https://www.rhea-db.org/help/license-disclaimer.
