Metadata-Version: 2.1
Name: bio-past
Version: 1.6.3
Summary: PAST: latent feature extraction with a Prior-based self-Attention framework for Spatial Transcriptomics
Home-page: https://github.com/lizhen18THU/PAST
Author: Zhen Li
Author-email: lizhen18@tsinghua.org.cn
License: MIT License
Keywords: pip,past
Platform: UNKNOWN
Classifier: Intended Audience :: Science/Research
Classifier: License :: OSI Approved :: MIT License
Classifier: Programming Language :: Python :: 3.8
Classifier: Operating System :: MacOS :: MacOS X
Classifier: Operating System :: Microsoft :: Windows
Classifier: Operating System :: POSIX :: Linux
Classifier: Topic :: Scientific/Engineering :: Bio-Informatics
Requires-Python: >3.6.0
License-File: LICENSE

PAST software is build on a variational graph convolutional auto-encoder designed for spatial transcriptomics which integrates prior information with Bayesian neural network, captures spatial information with self-attention mechanism and enables scalable application with ripple walk sampler strategy. PAST could effectively characterize spatial domains and facilitate various downstream analysis through integrating spatial information and reference from various sources. Besides, PAST also enable time and memory-efficient application on large datasets while preserving global spatial patterns for better performance. Importantly, PAST could also facilitate accurate annotation of spatial domains and thus provide biological insights.

