Metadata-Version: 2.4
Name: iskakov
Version: 0.2.0
Summary: Alias for own-baseline: does a single-cell potency score add anything beyond its own low-order primitive?
Author: Damir Iskakov
License: MIT License
        
        Copyright (c) 2026 Damir Iskakov
        
        Permission is hereby granted, free of charge, to any person obtaining a copy
        of this software and associated documentation files (the "Software"), to deal
        in the Software without restriction, including without limitation the rights
        to use, copy, modify, merge, publish, distribute, sublicense, and/or sell
        copies of the Software, and to permit persons to whom the Software is
        furnished to do so, subject to the following conditions:
        
        The above copyright notice and this permission notice shall be included in all
        copies or substantial portions of the Software.
        
        THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
        IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
        FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE
        AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
        LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM,
        OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE
        SOFTWARE.
        
Project-URL: Homepage, https://iskakov.dev/ownbaseline
Project-URL: Repository, https://github.com/IskakovDamir/ownbaseline
Project-URL: Issues, https://github.com/IskakovDamir/ownbaseline/issues
Keywords: single-cell,scRNA-seq,potency,stemness,benchmarking,incremental-validity,null-calibration,CytoTRACE,SCENT
Classifier: Development Status :: 4 - Beta
Classifier: Environment :: Console
Classifier: Intended Audience :: Science/Research
Classifier: License :: OSI Approved :: MIT License
Classifier: Operating System :: OS Independent
Classifier: Programming Language :: Python :: 3
Classifier: Programming Language :: Python :: 3.10
Classifier: Programming Language :: Python :: 3.11
Classifier: Programming Language :: Python :: 3.12
Classifier: Programming Language :: Python :: 3.13
Classifier: Topic :: Scientific/Engineering :: Bio-Informatics
Requires-Python: >=3.10
Description-Content-Type: text/markdown
License-File: LICENSE
Requires-Dist: own-baseline>=0.2.0
Dynamic: license-file

# iskakov

`pip install iskakov` installs [`own-baseline`](https://pypi.org/project/own-baseline/)
and gives you its command line under a second name. The two names run the same
program:

```bash
pip install iskakov

iskakov    check cells.h5ad --score obs:ccat --ordinal obs:stage \
                            --primitive degree-corr --ordinal-source experimental
ownbaseline check ...        # identical
```

Import the real package in scripts:

```python
from own_baseline import conditional_skill_report
```

## What the tool does

A potency score is supposed to order single cells by developmental potential.
Most published scores are built on a low-order primitive of the same expression
matrix: the number of genes detected, the correlation of a cell's profile with
network node degree, the Shannon entropy of the profile, the library size.
`own-baseline` asks whether the score orders a held-out ordinal any better than
that primitive does on its own. It rank-residualizes the score on its
author-declared primitive, takes Kendall's tau_b against the ordinal, and
compares the result against a measured floor from a 200-seed null grid indexed
by sample size, rank correlation, kernel and covariate count. The floor table
ships inside the wheel, so the answer does not depend on a network call.

Four verbs: `check`, `floors`, `primitives`, `verify`.

## Where the code lives

Source, tests, the null grid and the documentation are in the `own-baseline`
repository. This distribution is 60 lines of forwarding.

MIT licensed.
