// Created by libAntimony v2.13.0
function tumor_growth_0(g, T)
  g*T;
end

tumor_growth_0 is "tumor growth"

function kill(k, I)
  k*I;
end

kill is "kill"

function immune_stim(l, T, I)
  l*T*I;
end

immune_stim is "immune stim"


model *Babbs2012___immunotherapy()

  // Compartments and Species:
  compartment tumor_microenvironment;
  species T in tumor_microenvironment, I in tumor_microenvironment;

  // Reactions:
  tumor_growth:  => T; tumor_microenvironment*tumor_growth_0(g, T);
  tumor_killing: T => ; tumor_microenvironment*kill(k, I);
  immune_stimulation:  => I; tumor_microenvironment*immune_stim(l, T, I);
  immune_death: I => ; tumor_microenvironment*u*I;

  // Species initializations:
  T = 1;
  T has substance_per_volume;
  I = 0.001;
  I has substance_per_volume;

  // Compartment initializations:
  tumor_microenvironment = 1;
  tumor_microenvironment has volume;

  // Variable initializations:
  g = 0.004;
  g has unit_0;
  k = 4;
  k has unit_0;
  l = 0.09;
  l has unit_0;
  u = 0.1;
  u has unit_0;

  // Other declarations:
  const tumor_microenvironment, g, k, l, u;

  // Unit definitions:
  unit length = metre;
  unit area = metre^2;
  unit volume = 1e-3 litre;
  unit time_unit = time_unit;
  unit substance = 1e-3 mole;
  unit unit_0 = 1 / 86400e-1 second;
  unit extent = substance;
  unit substance_per_volume = 1e-3 mole / 1e-3 litre;

  // Display Names:
  time_unit is "time";
  unit_0 is "1/d";
  tumor_microenvironment is "tumor microenvironment";
  tumor_growth is "tumor growth";
  tumor_killing is "tumor killing";
  immune_stimulation is "immune stimulation";
  immune_death is "immune death";

  // CV terms:
  tumor_microenvironment hypernym "http://identifiers.org/ncit/C94498"
  T hypernym "http://identifiers.org/cl/CL:0001064"
  T hypernym "http://identifiers.org/ncit/C120284"
  I hypernym "http://identifiers.org/cl/CL:0000911"
  g hypernym "http://identifiers.org/sbo/SBO:0000610"
  k hypernym "http://identifiers.org/ncit/C25636"
  l hypernym "http://identifiers.org/ncit/C25636"
  u hypernym "http://identifiers.org/ncit/C25636"
  tumor_growth hypernym "http://identifiers.org/t3db/SBO:0000393"
  tumor_growth hypernym "http://identifiers.org/go/GO:0008283"
  tumor_killing hypernym "http://identifiers.org/sbo/SBO:0000179"
  tumor_killing hypernym "http://identifiers.org/go/GO:0002419"
  tumor_killing hypernym "http://identifiers.org/go/GO:0008219"
  immune_stimulation hypernym "http://identifiers.org/sbo/SBO:0000393"
  immune_stimulation hypernym "http://identifiers.org/go/GO:0070661"
  immune_death hypernym "http://identifiers.org/go/GO:0008219"
  immune_death hypernym "http://identifiers.org/sbo/SBO:0000179"
end

Babbs2012___immunotherapy is "Babbs2012 - immunotherapy"

Babbs2012___immunotherapy description "http://identifiers.org/pubmed/22432059"
Babbs2012___immunotherapy model_entity_is "http://identifiers.org/biomodels.db/MODEL1907240002",
                                          "http://identifiers.org/biomodels.db/BIOMD0000000758"
Babbs2012___immunotherapy property "http://identifiers.org/ncit/C15438"
Babbs2012___immunotherapy property "http://identifiers.org/go/GO:0002418"
Babbs2012___immunotherapy property "http://identifiers.org/mamo/MAMO_0000046"
Babbs2012___immunotherapy taxon "http://identifiers.org/taxonomy/9606"
