// Created by libAntimony v2.13.0
function function_4_IR_beta_phosphorylation_by_Insulin(IR_beta, IR_beta_phosphorylation_by_Insulin, Insulin)
  IR_beta_phosphorylation_by_Insulin*IR_beta*Insulin;
end

function_4_IR_beta_phosphorylation_by_Insulin is "function_4_IR_beta_phosphorylation_by_Insulin"

function function_4_IRS1_phosphorylation_by_IR_beta_pY1146(IRS1, IRS1_phosphorylation_by_IR_beta_pY1146, IR_beta_pY1146)
  IRS1_phosphorylation_by_IR_beta_pY1146*IRS1*IR_beta_pY1146;
end

function_4_IRS1_phosphorylation_by_IR_beta_pY1146 is "function_4_IRS1_phosphorylation_by_IR_beta_pY1146"

function function_4_IRS1_p_phosphorylation_by_p70S6K_pT389(IRS1_p, IRS1_p_phosphorylation_by_p70S6K_pT389, p70S6K_pT389)
  IRS1_p_phosphorylation_by_p70S6K_pT389*IRS1_p*p70S6K_pT389;
end

function_4_IRS1_p_phosphorylation_by_p70S6K_pT389 is "function_4_IRS1_p_phosphorylation_by_p70S6K_pT389"

function function_4_AMPK_T172_phosphorylation(AMPK, AMPK_T172_phosphorylation, IRS1_p)
  AMPK_T172_phosphorylation*AMPK*IRS1_p;
end

function_4_AMPK_T172_phosphorylation is "function_4_AMPK_T172_phosphorylation"

function function_4_Akt_S473_phosphorylation_by_mTORC2_pS2481_n_IRS1_p(Akt_S473, Akt_S473_phosphorylation_by_mTORC2_pS2481_n_IRS1_p, IRS1_p, mTORC2_pS2481)
  Akt_S473_phosphorylation_by_mTORC2_pS2481_n_IRS1_p*Akt_S473*mTORC2_pS2481*IRS1_p;
end

function_4_Akt_S473_phosphorylation_by_mTORC2_pS2481_n_IRS1_p is "function_4_Akt_S473_phosphorylation_by_mTORC2_pS2481_n_IRS1_p"

function function_4_Akt_T308_phosphorylation_by_IRS1_p(Akt_T308, Akt_T308_phosphorylation_by_IRS1_p, IRS1_p)
  Akt_T308_phosphorylation_by_IRS1_p*Akt_T308*IRS1_p;
end

function_4_Akt_T308_phosphorylation_by_IRS1_p is "function_4_Akt_T308_phosphorylation_by_IRS1_p"

function function_4_mTORC1_pS2448_dephosphorylation_by_TSC1_TSC2_pS1387(TSC1_TSC2_pS1387, mTORC1_pS2448, mTORC1_pS2448_dephosphorylation_by_TSC1_TSC2_pS1387)
  mTORC1_pS2448_dephosphorylation_by_TSC1_TSC2_pS1387*mTORC1_pS2448*TSC1_TSC2_pS1387;
end

function_4_mTORC1_pS2448_dephosphorylation_by_TSC1_TSC2_pS1387 is "function_4_mTORC1_pS2448_dephosphorylation_by_TSC1_TSC2_pS1387"

function function_4_mTORC1_S2448_activation_by_Amino_Acids(Amino_Acids, mTORC1, mTORC1_S2448_activation_by_Amino_Acids)
  mTORC1_S2448_activation_by_Amino_Acids*mTORC1*Amino_Acids;
end

function_4_mTORC1_S2448_activation_by_Amino_Acids is "function_4_mTORC1_S2448_activation_by_Amino_Acids"

function function_4_mTORC2_S2481_phosphorylation_by_PI3K_variant_p(PI3K_variant_p, mTORC2, mTORC2_S2481_phosphorylation_by_PI3K_variant_p)
  mTORC2_S2481_phosphorylation_by_PI3K_variant_p*mTORC2*PI3K_variant_p;
end

function_4_mTORC2_S2481_phosphorylation_by_PI3K_variant_p is "function_4_mTORC2_S2481_phosphorylation_by_PI3K_variant_p"

function function_4_p70S6K_T389_phosphorylation_by_mTORC1_pS2448(mTORC1_pS2448, p70S6K, p70S6K_T389_phosphorylation_by_mTORC1_pS2448)
  p70S6K_T389_phosphorylation_by_mTORC1_pS2448*p70S6K*mTORC1_pS2448;
end

function_4_p70S6K_T389_phosphorylation_by_mTORC1_pS2448 is "function_4_p70S6K_T389_phosphorylation_by_mTORC1_pS2448"

function function_4_PRAS40_S183_phosphorylation_by_mTORC1_pS2448(PRAS40_S183, PRAS40_S183_phosphorylation_by_mTORC1_pS2448, mTORC1_pS2448)
  PRAS40_S183_phosphorylation_by_mTORC1_pS2448*PRAS40_S183*mTORC1_pS2448;
end

function_4_PRAS40_S183_phosphorylation_by_mTORC1_pS2448 is "function_4_PRAS40_S183_phosphorylation_by_mTORC1_pS2448"

function function_4_PRAS40_T246_phosphorylation_by_Akt_pT308(Akt_pT308, PRAS40_T246, PRAS40_T246_phosphorylation_by_Akt_pT308)
  PRAS40_T246_phosphorylation_by_Akt_pT308*PRAS40_T246*Akt_pT308;
end

function_4_PRAS40_T246_phosphorylation_by_Akt_pT308 is "function_4_PRAS40_T246_phosphorylation_by_Akt_pT308"

function function_4_TSC1_TSC2_S1387_phosphorylation_by_AMPK_pT172(AMPK_pT172, TSC1_TSC2_S1387_phosphorylation_by_AMPK_pT172, TSC1_TSC2_pT1462)
  TSC1_TSC2_S1387_phosphorylation_by_AMPK_pT172*TSC1_TSC2_pT1462*AMPK_pT172;
end

function_4_TSC1_TSC2_S1387_phosphorylation_by_AMPK_pT172 is "function_4_TSC1_TSC2_S1387_phosphorylation_by_AMPK_pT172"

function function_4_TSC1_TSC2_T1462_phosphorylation_by_Akt_pT308(Akt_pT308, TSC1_TSC2_T1462_phosphorylation_by_Akt_pT308, TSC1_TSC2_pS1387)
  TSC1_TSC2_T1462_phosphorylation_by_Akt_pT308*TSC1_TSC2_pS1387*Akt_pT308;
end

function_4_TSC1_TSC2_T1462_phosphorylation_by_Akt_pT308 is "function_4_TSC1_TSC2_T1462_phosphorylation_by_Akt_pT308"

function function_4_PI3K_variant_phosphorylation_by_IR_beta_pY1146(IR_beta_pY1146, PI3K_variant, PI3K_variant_phosphorylation_by_IR_beta_pY1146)
  PI3K_variant_phosphorylation_by_IR_beta_pY1146*PI3K_variant*IR_beta_pY1146;
end

function_4_PI3K_variant_phosphorylation_by_IR_beta_pY1146 is "function_4_PI3K_variant_phosphorylation_by_IR_beta_pY1146"


model *MODEL1506230002()

  // Compartments and Species:
  compartment Cell;
  species IR_beta in Cell, IR_beta_pY1146 in Cell, IR_beta_refractory in Cell;
  species IRS1 in Cell, IRS1_p in Cell, IRS1_pS636 in Cell, AMPK in Cell;
  species AMPK_pT172 in Cell, Akt_T308 in Cell, Akt_pT308 in Cell, Akt_S473 in Cell;
  species Akt_pS473 in Cell, mTORC1 in Cell, mTORC1_pS2448 in Cell, mTORC2 in Cell;
  species mTORC2_pS2481 in Cell, p70S6K in Cell, p70S6K_pT389 in Cell, PRAS40_T246 in Cell;
  species PRAS40_pT246 in Cell, PRAS40_S183 in Cell, PRAS40_pS183 in Cell;
  species TSC1_TSC2_pT1462 in Cell, TSC1_TSC2_pS1387 in Cell, PI3K_variant in Cell;
  species PI3K_variant_p in Cell, $Insulin in Cell, $Amino_Acids in Cell;
  species $IR_beta_pY1146_obs in Cell, $IRS1_pS636_obs in Cell, $AMPK_pT172_obs in Cell;
  species $Akt_pT308_obs in Cell, $Akt_pS473_obs in Cell, $TSC1_TSC2_pS1387_obs in Cell;
  species $mTOR_pS2448_obs in Cell, $mTOR_pS2481_obs in Cell, $p70S6K_pT389_obs in Cell;
  species $PRAS40_pT246_obs in Cell, $PRAS40_pS183_obs in Cell;

  // Assignment Rules:
  Insulin := piecewise(0, time < -1, piecewise(0, time < 0, 10));
  Amino_Acids := piecewise(0, time < -1, piecewise(0, time < 0, 10));
  IR_beta_pY1146_obs := scale_IR_beta_pY1146_obs*IR_beta_pY1146;
  IRS1_pS636_obs := scale_IRS1_pS636_obs*IRS1_pS636;
  AMPK_pT172_obs := scale_AMPK_pT172_obs*AMPK_pT172;
  Akt_pT308_obs := scale_Akt_pT308_obs*Akt_pT308;
  Akt_pS473_obs := scale_Akt_pS473_obs*Akt_pS473;
  TSC1_TSC2_pS1387_obs := scale_TSC1_TSC2_pS1387_obs*TSC1_TSC2_pS1387;
  mTOR_pS2448_obs := scale_mTOR_pS2448_obs*mTORC1_pS2448;
  mTOR_pS2481_obs := scale_mTOR_pS2481_obs*mTORC2_pS2481;
  p70S6K_pT389_obs := scale_p70S6K_pT389_obs*p70S6K_pT389;
  PRAS40_pT246_obs := scale_PRAS40_pT246_obs*PRAS40_pT246;
  PRAS40_pS183_obs := scale_PRAS40_pS183_obs*PRAS40_pS183;

  // Reactions:
  reaction_1: IR_beta => IR_beta_pY1146; Cell*function_4_IR_beta_phosphorylation_by_Insulin(IR_beta, IR_beta_phosphorylation_by_Insulin, Insulin);
  reaction_2: IR_beta_pY1146 => IR_beta_refractory; Cell*IR_beta_pY1146_dephosphorylation*IR_beta_pY1146;
  reaction_3: IR_beta_refractory => IR_beta; Cell*IR_beta_ready*IR_beta_refractory;
  reaction_4: IRS1 => IRS1_p; Cell*function_4_IRS1_phosphorylation_by_IR_beta_pY1146(IRS1, IRS1_phosphorylation_by_IR_beta_pY1146, IR_beta_pY1146);
  reaction_5: IRS1_p => IRS1_pS636; Cell*function_4_IRS1_p_phosphorylation_by_p70S6K_pT389(IRS1_p, IRS1_p_phosphorylation_by_p70S6K_pT389, p70S6K_pT389);
  reaction_6: IRS1_pS636 => IRS1; Cell*IRS1_pS636_dephosphorylation*IRS1_pS636;
  reaction_7: AMPK => AMPK_pT172; Cell*function_4_AMPK_T172_phosphorylation(AMPK, AMPK_T172_phosphorylation, IRS1_p);
  reaction_8: AMPK_pT172 => AMPK; Cell*AMPK_pT172_dephosphorylation*AMPK_pT172;
  reaction_9: Akt_pT308 => Akt_T308; Cell*Akt_pT308_dephosphorylation*Akt_pT308;
  reaction_10: Akt_pS473 => Akt_S473; Cell*Akt_pS473_dephosphorylation*Akt_pS473;
  reaction_11: Akt_S473 => Akt_pS473; Cell*function_4_Akt_S473_phosphorylation_by_mTORC2_pS2481_n_IRS1_p(Akt_S473, Akt_S473_phosphorylation_by_mTORC2_pS2481_n_IRS1_p, IRS1_p, mTORC2_pS2481);
  reaction_12: Akt_T308 => Akt_pT308; Cell*function_4_Akt_T308_phosphorylation_by_IRS1_p(Akt_T308, Akt_T308_phosphorylation_by_IRS1_p, IRS1_p);
  reaction_13: mTORC1_pS2448 => mTORC1; Cell*function_4_mTORC1_pS2448_dephosphorylation_by_TSC1_TSC2_pS1387(TSC1_TSC2_pS1387, mTORC1_pS2448, mTORC1_pS2448_dephosphorylation_by_TSC1_TSC2_pS1387);
  reaction_14: mTORC1 => mTORC1_pS2448; Cell*function_4_mTORC1_S2448_activation_by_Amino_Acids(Amino_Acids, mTORC1, mTORC1_S2448_activation_by_Amino_Acids);
  reaction_15: mTORC2_pS2481 => mTORC2; Cell*mTORC2_pS2481_dephosphorylation*mTORC2_pS2481;
  reaction_16: mTORC2 => mTORC2_pS2481; Cell*function_4_mTORC2_S2481_phosphorylation_by_PI3K_variant_p(PI3K_variant_p, mTORC2, mTORC2_S2481_phosphorylation_by_PI3K_variant_p);
  reaction_17: p70S6K_pT389 => p70S6K; Cell*p70S6K_pT389_dephosphorylation*p70S6K_pT389;
  reaction_18: p70S6K => p70S6K_pT389; Cell*function_4_p70S6K_T389_phosphorylation_by_mTORC1_pS2448(mTORC1_pS2448, p70S6K, p70S6K_T389_phosphorylation_by_mTORC1_pS2448);
  reaction_19: PRAS40_pS183 => PRAS40_S183; Cell*PRAS40_pS183_dephosphorylation*PRAS40_pS183;
  reaction_20: PRAS40_pT246 => PRAS40_T246; Cell*PRAS40_pT246_dephosphorylation*PRAS40_pT246;
  reaction_21: PRAS40_S183 => PRAS40_pS183; Cell*function_4_PRAS40_S183_phosphorylation_by_mTORC1_pS2448(PRAS40_S183, PRAS40_S183_phosphorylation_by_mTORC1_pS2448, mTORC1_pS2448);
  reaction_22: PRAS40_T246 => PRAS40_pT246; Cell*function_4_PRAS40_T246_phosphorylation_by_Akt_pT308(Akt_pT308, PRAS40_T246, PRAS40_T246_phosphorylation_by_Akt_pT308);
  reaction_23: TSC1_TSC2_pT1462 => TSC1_TSC2_pS1387; Cell*function_4_TSC1_TSC2_S1387_phosphorylation_by_AMPK_pT172(AMPK_pT172, TSC1_TSC2_S1387_phosphorylation_by_AMPK_pT172, TSC1_TSC2_pT1462);
  reaction_24: TSC1_TSC2_pS1387 => TSC1_TSC2_pT1462; Cell*function_4_TSC1_TSC2_T1462_phosphorylation_by_Akt_pT308(Akt_pT308, TSC1_TSC2_T1462_phosphorylation_by_Akt_pT308, TSC1_TSC2_pS1387);
  reaction_25: PI3K_variant_p => PI3K_variant; Cell*PI3K_variant_p_dephosphorylation*PI3K_variant_p;
  reaction_26: PI3K_variant => PI3K_variant_p; Cell*function_4_PI3K_variant_phosphorylation_by_IR_beta_pY1146(IR_beta_pY1146, PI3K_variant, PI3K_variant_phosphorylation_by_IR_beta_pY1146);

  // Species initializations:
  IR_beta = 16.5607;
  IR_beta_pY1146 = 0;
  IR_beta_refractory = 0;
  IRS1 = 18.9345;
  IRS1_p = 0;
  IRS1_pS636 = 0;
  AMPK = 20.5064;
  AMPK_pT172 = 0;
  Akt_T308 = 21.4109;
  Akt_pT308 = 0;
  Akt_S473 = 12.2517;
  Akt_pS473 = 0;
  mTORC1 = 25.14;
  mTORC1_pS2448 = 0;
  mTORC2 = 18.7959;
  mTORC2_pS2481 = 0;
  p70S6K = 14.301;
  p70S6K_pT389 = 0;
  PRAS40_T246 = 13.5613;
  PRAS40_pT246 = 0;
  PRAS40_S183 = 17.55;
  PRAS40_pS183 = 0;
  TSC1_TSC2_pT1462 = 14.9175;
  TSC1_TSC2_pS1387 = 0;
  PI3K_variant = 18.9345;
  PI3K_variant_p = 0;

  // Compartment initializations:
  Cell = 1;

  // Variable initializations:
  scale_IR_beta_pY1146_obs = 1;
  scale_IRS1_pS636_obs = 1;
  scale_AMPK_pT172_obs = 1;
  scale_Akt_pT308_obs = 1;
  scale_Akt_pS473_obs = 1;
  scale_TSC1_TSC2_pS1387_obs = 1;
  scale_mTOR_pS2448_obs = 1;
  scale_mTOR_pS2481_obs = 1;
  scale_p70S6K_pT389_obs = 1;
  scale_PRAS40_pT246_obs = 1;
  scale_PRAS40_pS183_obs = 1;
  IR_beta_phosphorylation_by_Insulin = 0.124273166818913;
  IR_beta_pY1146_dephosphorylation = 0.396235078561935;
  IR_beta_ready = 0.0532769862975496;
  IRS1_phosphorylation_by_IR_beta_pY1146 = 0.00491598674814158;
  IRS1_p_phosphorylation_by_p70S6K_pT389 = 1682.74838380846;
  IRS1_pS636_dephosphorylation = 0.0130499987407289;
  AMPK_T172_phosphorylation = 9.79765849087796;
  AMPK_pT172_dephosphorylation = 0.0107214736590526;
  Akt_pT308_dephosphorylation = 0.00335544587646129;
  Akt_pS473_dephosphorylation = 0.00640215551178824;
  Akt_S473_phosphorylation_by_mTORC2_pS2481_n_IRS1_p = 13.1441708920036;
  Akt_T308_phosphorylation_by_IRS1_p = 6.91810637938108;
  mTORC1_pS2448_dephosphorylation_by_TSC1_TSC2_pS1387 = 0.0106651971237991;
  mTORC1_S2448_activation_by_Amino_Acids = 0.00438915524637669;
  mTORC2_pS2481_dephosphorylation = 0.0183734532316308;
  mTORC2_S2481_phosphorylation_by_PI3K_variant_p = 0.37535264623552;
  p70S6K_pT389_dephosphorylation = 0.0113511588360422;
  p70S6K_T389_phosphorylation_by_mTORC1_pS2448 = 0.00184042775983938;
  PRAS40_pS183_dephosphorylation = 2.33014390064544;
  PRAS40_pT246_dephosphorylation = 1.60512543108081;
  PRAS40_S183_phosphorylation_by_mTORC1_pS2448 = 0.187621138099883;
  PRAS40_T246_phosphorylation_by_Akt_pT308 = 0.137729484208433;
  TSC1_TSC2_S1387_phosphorylation_by_AMPK_pT172 = 0.036558856656738;
  TSC1_TSC2_T1462_phosphorylation_by_Akt_pT308 = 0.0177561800881718;
  PI3K_variant_p_dephosphorylation = 10;
  PI3K_variant_phosphorylation_by_IR_beta_pY1146 = 0.01;

  // Other declarations:
  const Cell, scale_IR_beta_pY1146_obs, scale_IRS1_pS636_obs, scale_AMPK_pT172_obs;
  const scale_Akt_pT308_obs, scale_Akt_pS473_obs, scale_TSC1_TSC2_pS1387_obs;
  const scale_mTOR_pS2448_obs, scale_mTOR_pS2481_obs, scale_p70S6K_pT389_obs;
  const scale_PRAS40_pT246_obs, scale_PRAS40_pS183_obs, IR_beta_phosphorylation_by_Insulin;
  const IR_beta_pY1146_dephosphorylation, IR_beta_ready, IRS1_phosphorylation_by_IR_beta_pY1146;
  const IRS1_p_phosphorylation_by_p70S6K_pT389, IRS1_pS636_dephosphorylation;
  const AMPK_T172_phosphorylation, AMPK_pT172_dephosphorylation, Akt_pT308_dephosphorylation;
  const Akt_pS473_dephosphorylation, Akt_S473_phosphorylation_by_mTORC2_pS2481_n_IRS1_p;
  const Akt_T308_phosphorylation_by_IRS1_p, mTORC1_pS2448_dephosphorylation_by_TSC1_TSC2_pS1387;
  const mTORC1_S2448_activation_by_Amino_Acids, mTORC2_pS2481_dephosphorylation;
  const mTORC2_S2481_phosphorylation_by_PI3K_variant_p, p70S6K_pT389_dephosphorylation;
  const p70S6K_T389_phosphorylation_by_mTORC1_pS2448, PRAS40_pS183_dephosphorylation;
  const PRAS40_pT246_dephosphorylation, PRAS40_S183_phosphorylation_by_mTORC1_pS2448;
  const PRAS40_T246_phosphorylation_by_Akt_pT308, TSC1_TSC2_S1387_phosphorylation_by_AMPK_pT172;
  const TSC1_TSC2_T1462_phosphorylation_by_Akt_pT308, PI3K_variant_p_dephosphorylation;
  const PI3K_variant_phosphorylation_by_IR_beta_pY1146;

  // Unit definitions:
  unit volume = dimensionless;
  unit time_unit = 60 second;
  unit substance = dimensionless;

  // Display Names:
  time_unit is "time";
  reaction_1 is "IR_beta_phosphorylation_by_Insulin";
  reaction_2 is "IR_beta_pY1146_dephosphorylation";
  reaction_3 is "IR_beta_ready";
  reaction_4 is "IRS1_phosphorylation_by_IR_beta_pY1146";
  reaction_5 is "IRS1_p_phosphorylation_by_p70S6K_pT389";
  reaction_6 is "IRS1_pS636_dephosphorylation";
  reaction_7 is "AMPK_T172_phosphorylation";
  reaction_8 is "AMPK_pT172_dephosphorylation";
  reaction_9 is "Akt_pT308_dephosphorylation";
  reaction_10 is "Akt_pS473_dephosphorylation";
  reaction_11 is "Akt_S473_phosphorylation_by_mTORC2_pS2481_n_IRS1_p";
  reaction_12 is "Akt_T308_phosphorylation_by_IRS1_p";
  reaction_13 is "mTORC1_pS2448_dephosphorylation_by_TSC1_TSC2_pS1387";
  reaction_14 is "mTORC1_S2448_activation_by_Amino_Acids";
  reaction_15 is "mTORC2_pS2481_dephosphorylation";
  reaction_16 is "mTORC2_S2481_phosphorylation_by_PI3K_variant_p";
  reaction_17 is "p70S6K_pT389_dephosphorylation";
  reaction_18 is "p70S6K_T389_phosphorylation_by_mTORC1_pS2448";
  reaction_19 is "PRAS40_pS183_dephosphorylation";
  reaction_20 is "PRAS40_pT246_dephosphorylation";
  reaction_21 is "PRAS40_S183_phosphorylation_by_mTORC1_pS2448";
  reaction_22 is "PRAS40_T246_phosphorylation_by_Akt_pT308";
  reaction_23 is "TSC1_TSC2_S1387_phosphorylation_by_AMPK_pT172";
  reaction_24 is "TSC1_TSC2_T1462_phosphorylation_by_Akt_pT308";
  reaction_25 is "PI3K_variant_p_dephosphorylation";
  reaction_26 is "PI3K_variant_phosphorylation_by_IR_beta_pY1146";

  // CV terms:
  Cell hypernym "http://identifiers.org/bto/BTO:0000567"
  IR_beta identity "http://identifiers.org/uniprot/P06213"
  IR_beta_pY1146 identity "http://identifiers.org/uniprot/P06213"
  IR_beta_refractory identity "http://identifiers.org/uniprot/P06213"
  IRS1 parthood "http://identifiers.org/uniprot/P35568"
  IRS1 parthood "http://identifiers.org/uniprot/P42336"
  IRS1_p parthood "http://identifiers.org/uniprot/P35568"
  IRS1_p parthood "http://identifiers.org/uniprot/P42336"
  IRS1_pS636 parthood "http://identifiers.org/uniprot/P35568"
  IRS1_pS636 parthood "http://identifiers.org/uniprot/P42336"
  AMPK parthood "http://identifiers.org/uniprot/Q9Y478"
  AMPK parthood "http://identifiers.org/uniprot/P54619"
  AMPK parthood "http://identifiers.org/uniprot/Q13131"
  AMPK_pT172 parthood "http://identifiers.org/uniprot/P54619"
  AMPK_pT172 parthood "http://identifiers.org/uniprot/Q9Y478"
  AMPK_pT172 parthood "http://identifiers.org/uniprot/Q13131"
  Akt_T308 identity "http://identifiers.org/uniprot/P31749"
  Akt_pT308 identity "http://identifiers.org/uniprot/P31749"
  Akt_S473 identity "http://identifiers.org/uniprot/P31749"
  Akt_pS473 identity "http://identifiers.org/uniprot/P31749"
  mTORC1 identity "http://identifiers.org/uniprot/P42345"
  mTORC1_pS2448 identity "http://identifiers.org/uniprot/P42345"
  mTORC2 identity "http://identifiers.org/uniprot/P42345"
  mTORC2_pS2481 identity "http://identifiers.org/uniprot/P42345"
  p70S6K identity "http://identifiers.org/uniprot/P23443"
  p70S6K_pT389 identity "http://identifiers.org/uniprot/P23443"
  PRAS40_T246 identity "http://identifiers.org/uniprot/Q96B36"
  PRAS40_pT246 identity "http://identifiers.org/uniprot/Q96B36"
  PRAS40_S183 identity "http://identifiers.org/uniprot/Q96B36"
  PRAS40_pS183 identity "http://identifiers.org/uniprot/Q96B36"
  TSC1_TSC2_pT1462 parthood "http://identifiers.org/uniprot/Q92574"
  TSC1_TSC2_pT1462 parthood "http://identifiers.org/uniprot/P49815"
  TSC1_TSC2_pS1387 parthood "http://identifiers.org/uniprot/P49815"
  TSC1_TSC2_pS1387 parthood "http://identifiers.org/uniprot/Q92574"
  Insulin identity "http://identifiers.org/uniprot/P01308"
  IR_beta_pY1146_obs identity "http://identifiers.org/uniprot/P06213"
  IRS1_pS636_obs parthood "http://identifiers.org/uniprot/P42336"
  IRS1_pS636_obs parthood "http://identifiers.org/uniprot/P35568"
  AMPK_pT172_obs parthood "http://identifiers.org/uniprot/P54619"
  AMPK_pT172_obs parthood "http://identifiers.org/uniprot/Q13131"
  AMPK_pT172_obs parthood "http://identifiers.org/uniprot/Q9Y478"
  Akt_pT308_obs identity "http://identifiers.org/uniprot/P31749"
  Akt_pS473_obs identity "http://identifiers.org/uniprot/P31749"
  TSC1_TSC2_pS1387_obs parthood "http://identifiers.org/uniprot/P49815"
  TSC1_TSC2_pS1387_obs parthood "http://identifiers.org/uniprot/Q92574"
  mTOR_pS2448_obs identity "http://identifiers.org/uniprot/P42345"
  mTOR_pS2481_obs identity "http://identifiers.org/uniprot/P42345"
  p70S6K_pT389_obs identity "http://identifiers.org/uniprot/P23443"
  PRAS40_pT246_obs identity "http://identifiers.org/uniprot/Q96B36"
  PRAS40_pS183_obs identity "http://identifiers.org/uniprot/Q96B36"
end

MODEL1506230002 is "Sonntag2012 - mTOR model - IRS dependent regulation of AMPK by insulin"

MODEL1506230002 model_entity_is "http://identifiers.org/biomodels.db/MODEL1506230002"
MODEL1506230002 model_entity_is "http://identifiers.org/biomodels.db/BIOMD0000000580"
MODEL1506230002 description "http://identifiers.org/pubmed/22452783"
MODEL1506230002 origin "http://identifiers.org/biomodels.db/BIOMD0000000581"
MODEL1506230002 container "http://identifiers.org/bto/BTO:0000567",
                          "http://identifiers.org/bto/BTO:0000165"
MODEL1506230002 taxon "http://identifiers.org/taxonomy/9606",
                      "http://identifiers.org/taxonomy/10090"
MODEL1506230002 hypernym "http://identifiers.org/go/GO:0032869",
                         "http://identifiers.org/go/GO:2000479"
