// Created by libAntimony v2.13.0
function function_1(k_syn_mRNA, species_7)
  k_syn_mRNA*species_7;
end

function_1 is "mRNA synthesis_1"

function function_3(k_syn_miRNA_2, species_9)
  k_syn_miRNA_2*species_9;
end

function_3 is "miRNA_2 synthesis_1"

function function_4(k_syn_prot, species_1)
  k_syn_prot*species_1;
end

function_4 is "protein synthesis_1"

function function_2(k_syn_miRNA_1, species_8)
  k_syn_miRNA_1*species_8;
end

function_2 is "miRNA_1 synthesis_1"


model *Model_1()

  // Compartments and Species:
  compartment compartment_1;
  species species_1 in compartment_1, species_2 in compartment_1, species_3 in compartment_1;
  species species_4 in compartment_1, species_5 in compartment_1, species_6 in compartment_1;
  species species_7 in compartment_1, species_8 in compartment_1, species_9 in compartment_1;
  species species_10 in compartment_1;

  // Reactions:
  reaction_1: species_1 + species_2 => species_4; compartment_1*reaction_1_k1*species_1*species_2;
  reaction_2: species_1 + species_3 => species_5; compartment_1*reaction_2_k1*species_1*species_3;
  reaction_3: species_1 + species_2 + species_3 => species_6; compartment_1*reaction_3_k1*species_1*species_2*species_3;
  reaction_4:  => species_1; compartment_1*function_1(reaction_4_k_syn_mRNA, species_7);
  reaction_5:  => species_2; compartment_1*function_2(reaction_5_k_syn_miRNA_1, species_8);
  reaction_6:  => species_3; compartment_1*function_3(reaction_6_k_syn_miRNA_2, species_9);
  reaction_7: species_1 => ; compartment_1*reaction_7_k1*species_1;
  reaction_8: species_2 => ; compartment_1*reaction_8_k1*species_2;
  reaction_9: species_3 => ; compartment_1*reaction_9_k1*species_3;
  reaction_10: species_4 => species_2 + species_1; compartment_1*reaction_10_k1*species_4;
  reaction_11: species_5 => species_3 + species_1; compartment_1*reaction_11_k1*species_5;
  reaction_12: species_6 => species_2 + species_3 + species_1; compartment_1*reaction_12_k1*species_6;
  reaction_13: species_4 => ; compartment_1*reaction_13_k1*species_4;
  reaction_14: species_5 => ; compartment_1*reaction_14_k1*species_5;
  reaction_15: species_6 => ; compartment_1*reaction_15_k1*species_6;
  reaction_16:  => species_10; compartment_1*function_4(reaction_16_k_syn_prot, species_1);
  reaction_17: species_10 => ; compartment_1*reaction_17_k1*species_10;

  // Species initializations:
  species_1 = 1;
  species_2 = 0;
  species_3 = 0;
  species_4 = 0;
  species_5 = 0;
  species_6 = 0;
  species_7 = 1;
  species_8 = 1;
  species_9 = 1;
  species_10 = 1;

  // Compartment initializations:
  compartment_1 = 1;

  // Variable initializations:
  reaction_1_k1 = 0.00045298;
  reaction_2_k1 = 1.30837e-05;
  reaction_3_k1 = 0.999534;
  reaction_4_k_syn_mRNA = 1;
  reaction_5_k_syn_miRNA_1 = 1;
  reaction_6_k_syn_miRNA_2 = 1;
  reaction_7_k1 = 1;
  reaction_8_k1 = 1;
  reaction_9_k1 = 1;
  reaction_10_k1 = 0.249955;
  reaction_11_k1 = 0.241033;
  reaction_12_k1 = 0.187796;
  reaction_13_k1 = 1;
  reaction_14_k1 = 1;
  reaction_15_k1 = 1;
  reaction_16_k_syn_prot = 1;
  reaction_17_k1 = 1;

  // Other declarations:
  const compartment_1;

  // Unit definitions:
  unit substance = 1e-3 mole;

  // Display Names:
  compartment_1 is "compartment";
  species_1 is "mRNA";
  species_2 is "miRNA_1";
  species_3 is "miRNA_2";
  species_4 is "duplex_1";
  species_5 is "duplex_2";
  species_6 is "triplex";
  species_7 is "TF_mRNA";
  species_8 is "TF_miRNA_1";
  species_9 is "TF_miRNA_2";
  species_10 is "protein";
  reaction_1 is "duplex 1 association";
  reaction_2 is "duplex 2 association";
  reaction_3 is "triplex association";
  reaction_4 is "mRNA synthesis";
  reaction_5 is "miRNA_1 synthesis";
  reaction_6 is "miRNA_2 synthesis";
  reaction_7 is "mRNA degradation";
  reaction_8 is "miRNA_1 degradation";
  reaction_9 is "miRNA_2 degradation";
  reaction_10 is "duplex 1 dissociation";
  reaction_11 is "duplex 2 dissociation";
  reaction_12 is "triplex dissociation";
  reaction_13 is "duplex 1 degradation";
  reaction_14 is "duplex 2 degradation";
  reaction_15 is "triplex degradation";
  reaction_16 is "protein synthesis";
  reaction_17 is "protein degradation";

  // CV terms:
  species_1 identity "http://identifiers.org/ensembl/ENSG00000151468"
  species_1 identity "http://identifiers.org/chebi/CHEBI:33699"
  species_2 identity "http://identifiers.org/mirbase/MI0003575"
  species_2 identity "http://identifiers.org/biomodels.sbo/SBO:0000316"
  species_3 identity "http://identifiers.org/mirbase/MI0000476"
  species_3 identity "http://identifiers.org/biomodels.sbo/SBO:0000316"
  species_4 part "http://identifiers.org/ensembl/ENSG00000151468"
  species_4 part "http://identifiers.org/mirbase/MI0003575"
  species_5 part "http://identifiers.org/ensembl/ENSG00000151468"
  species_5 part "http://identifiers.org/mirbase/MI0000476"
  species_6 part "http://identifiers.org/ensembl/ENSG00000151468"
  species_6 part "http://identifiers.org/mirbase/MI0003575"
  species_6 part "http://identifiers.org/mirbase/MI0000476"
  species_10 encoder "http://identifiers.org/ensembl/ENSG00000151468"
end

Model_1 is "Schmitz2014 - RNA triplex formation"

Model_1 model_entity_is "http://identifiers.org/biomodels.db/MODEL1402210000"
Model_1 model_entity_is "http://identifiers.org/biomodels.db/BIOMD0000000530"
Model_1 description "http://identifiers.org/pubmed/24875477"
Model_1 hypernym "http://identifiers.org/go/GO:0010468"
Model_1 taxon "http://identifiers.org/taxonomy/9606"
