// Created by libAntimony v2.13.0
model *MODEL1212040001()

  // Compartments and Species:
  compartment compartment_;
  species R in compartment_, L in compartment_, RL in compartment_, Gabg in compartment_;
  species RGabg in compartment_, RGabgL in compartment_, GaGTP in compartment_;
  species Gbg in compartment_, RGS in compartment_, RGSGaGTP in compartment_;
  species GaGDPP in compartment_, Effector in compartment_, GaGTPEffector in compartment_;
  species inertGaGTP in compartment_, RGSinertGaGTP in compartment_, GaGDP in compartment_;
  species P in compartment_, z1 in compartment_, z2 in compartment_, z3 in compartment_;

  // Reactions:
  R1: R + L => RL; compartment_*R*L*R1_k1;
  R2: R + Gabg => RGabg; compartment_*R*Gabg*R2_k2;
  R3: RL + Gabg => RGabgL; compartment_*RL*Gabg*R3_k3;
  R4: RGabg + L => RGabgL; compartment_*RGabg*L*R4_k4;
  R5: RGabgL => RL + GaGTP + Gbg; compartment_*RGabgL*R5_k5;
  R6: Gabg => GaGTP + Gbg; compartment_*Gabg*R6_k6;
  R7: GaGTP + RGS => RGSGaGTP; compartment_*GaGTP*RGS*R7_k7;
  R8: RGSGaGTP => GaGDPP + RGS; compartment_*RGSGaGTP*R8_k8;
  R9: GaGTP => GaGDPP; compartment_*GaGTP*R9_k9;
  R10: Effector + GaGTP => GaGTPEffector; compartment_*Effector*GaGTP*R10_k10;
  R11: GaGTPEffector => inertGaGTP + Effector; compartment_*GaGTPEffector*R11_k11;
  R12: inertGaGTP + RGS => RGSinertGaGTP; compartment_*inertGaGTP*RGS*R12_k12;
  R13: RGSinertGaGTP => GaGDPP + RGS; compartment_*RGSinertGaGTP*R13_k13;
  R14: inertGaGTP => GaGDPP; compartment_*inertGaGTP*R14_k14;
  R15: GaGDPP => GaGDP + P; compartment_*GaGDPP*R15_k15;
  R16: GaGDP + Gbg => Gabg; compartment_*GaGDP*Gbg*R16_k16;
  R17: P => ; compartment_*P*R17_k17;
  R18:  => z1; compartment_*GaGTPEffector*ka;
  R19: z1 => z2; compartment_*z1*ka;
  R20: z2 => z3; compartment_*z2*ka;
  R21: z3 => ; compartment_*z3*ka;

  // Events:
  Ligand_addition: at time >= 14: L = L + Ligand_conc;

  // Species initializations:
  R = 205;
  R has nanoMolar;
  L = 0;
  L has nanoMolar;
  RL = 0;
  RL has nanoMolar;
  Gabg = 0;
  Gabg has nanoMolar;
  RGabg = 0;
  RGabg has nanoMolar;
  RGabgL = 0;
  RGabgL has nanoMolar;
  GaGTP = 0;
  GaGTP has nanoMolar;
  Gbg = 205;
  Gbg has nanoMolar;
  RGS = 60;
  RGS has nanoMolar;
  RGSGaGTP = 0;
  RGSGaGTP has nanoMolar;
  GaGDPP = 0;
  GaGDPP has nanoMolar;
  Effector = 205;
  Effector has nanoMolar;
  GaGTPEffector = 0;
  GaGTPEffector has nanoMolar;
  inertGaGTP = 0;
  inertGaGTP has nanoMolar;
  RGSinertGaGTP = 0;
  RGSinertGaGTP has nanoMolar;
  GaGDP = 205;
  GaGDP has nanoMolar;
  P = 0;
  P has nanoMolar;
  z1 = 0;
  z1 has nanoMolar;
  z2 = 0;
  z2 has nanoMolar;
  z3 = 0;
  z3 has nanoMolar;

  // Compartment initializations:
  compartment_ = 1;

  // Variable initializations:
  Ligand_conc = 0.1;
  Ligand_conc has nanoMolar;
  ka = 1.5;
  ka has FirstOrder;
  R1_k1 = 0.0025;
  R1_k1 has SecondOrder;
  R2_k2 = 0.005;
  R2_k2 has SecondOrder;
  R3_k3 = 0.02;
  R3_k3 has SecondOrder;
  R4_k4 = 0.005;
  R4_k4 has SecondOrder;
  R5_k5 = 50;
  R5_k5 has FirstOrder;
  R6_k6 = 0.2;
  R6_k6 has FirstOrder;
  R7_k7 = 500;
  R7_k7 has SecondOrder;
  R8_k8 = 2.5;
  R8_k8 has FirstOrder;
  R9_k9 = 0.005;
  R9_k9 has FirstOrder;
  R10_k10 = 10;
  R10_k10 has SecondOrder;
  R11_k11 = 1;
  R11_k11 has FirstOrder;
  R12_k12 = 50;
  R12_k12 has SecondOrder;
  R13_k13 = 0.3;
  R13_k13 has FirstOrder;
  R14_k14 = 0.005;
  R14_k14 has FirstOrder;
  R15_k15 = 1000;
  R15_k15 has FirstOrder;
  R16_k16 = 1000;
  R16_k16 has SecondOrder;
  R17_k17 = 10;
  R17_k17 has FirstOrder;

  // Other declarations:
  const compartment_, Ligand_conc, ka;

  // Unit definitions:
  unit nanoMolar = 1e-9 mole / litre;
  unit hour = 3600 second;
  unit FirstOrder = 1 / 3600 second;
  unit SecondOrder = litre / (1e-9 mole * 3600 second);
  unit nanoMolar_volume = 1e-9 mole;

  // Display Names:
  nanoMolar is "nM";
  hour is "hr";
  FirstOrder is "1/hr";
  SecondOrder is "1/(nM*hr)";
  compartment_ is "cell";
  R1 is "Receptor-Ligand association";
  R2 is "Receptor-Gprotein association";
  R3 is "RL-Gprotein association";
  R4 is "RGabg-Ligand association";
  R5 is "Galpha activation by receptor";
  R6 is "Galpha activation spontaneous";
  R7 is "Galpha-RGS association";
  R8 is "Galpha deactivation by RGS";
  R9 is "Galpha deactivation spontaneous";
  R10 is "Galpha-Effector association";
  R11 is "Galpha becomes inert";
  R12 is "inertGalpha-RGS association";
  R13 is "inertGalpha deactivation by RGS";
  R14 is "inertGalpha deactivation spontaneous";
  R15 is "Phosphate release";
  R16 is "Gprotein subunits association";
  R17 is "Phosphate degradation";
  R18 is "Delay 1";
  R19 is "Delay 2";
  R20 is "Delay 3";
  R21 is "Delay 4";

  // SBO terms:
  R.sboTerm = 244
  L.sboTerm = 280
  R1.sboTerm = 526
  R2.sboTerm = 526
  R3.sboTerm = 526
  R4.sboTerm = 526
  R7.sboTerm = 526
  R8.sboTerm = 169
  R9.sboTerm = 169
  R10.sboTerm = 526
  R11.sboTerm = 169
  R12.sboTerm = 526
  R13.sboTerm = 169
  R14.sboTerm = 169
  R15.sboTerm = 393
  R16.sboTerm = 526
  R17.sboTerm = 179
  R18.sboTerm = 225
  R19.sboTerm = 225
  R20.sboTerm = 225
  R21.sboTerm = 225

  // CV terms:
  compartment_ identity "http://identifiers.org/go/GO:0005623"
  R hypernym "http://identifiers.org/interpro/IPR000276"
  RL hypernym "http://identifiers.org/go/GO:0043235"
  Gabg hypernym "http://identifiers.org/go/GO:0005834"
  RGabg part "http://identifiers.org/interpro/IPR000276",
             "http://identifiers.org/go/GO:0005834"
  RGabgL part "http://identifiers.org/interpro/IPR000276",
              "http://identifiers.org/go/GO:0005834",
              "http://identifiers.org/biomodels.sbo/SBO:0000280"
  GaGTP part "http://identifiers.org/chebi/CHEBI:15996",
             "http://identifiers.org/uniprot/P04695"
  Gbg part "http://identifiers.org/uniprot/P62873",
           "http://identifiers.org/uniprot/P63211"
  RGS property "http://identifiers.org/interpro/IPR000342"
  RGSGaGTP part "http://identifiers.org/chebi/CHEBI:15996",
                "http://identifiers.org/uniprot/P04695",
                "http://identifiers.org/interpro/IPR000342"
  GaGDPP part "http://identifiers.org/chebi/CHEBI:17552",
              "http://identifiers.org/uniprot/P04695"
  Effector hypernym "http://identifiers.org/biomodels.sbo/SBO:0000459"
  GaGTPEffector part "http://identifiers.org/chebi/CHEBI:15996",
                     "http://identifiers.org/uniprot/P04695",
                     "http://identifiers.org/biomodels.sbo/SBO:0000459"
  inertGaGTP part "http://identifiers.org/chebi/CHEBI:15996",
                  "http://identifiers.org/uniprot/P04695"
  inertGaGTP property "http://identifiers.org/pato/PATO:0002355"
  RGSinertGaGTP part "http://identifiers.org/chebi/CHEBI:15996",
                     "http://identifiers.org/uniprot/P04695",
                     "http://identifiers.org/interpro/IPR000342"
  RGSinertGaGTP property "http://identifiers.org/pato/PATO:0002355"
  GaGDP part "http://identifiers.org/chebi/CHEBI:17552",
             "http://identifiers.org/uniprot/P04695"
  P hypernym "http://identifiers.org/chebi/CHEBI:18367"
  z1 hypernym "http://identifiers.org/biomodels.sbo/SBO:0000347"
  z2 hypernym "http://identifiers.org/biomodels.sbo/SBO:0000347"
  z3 hypernym "http://identifiers.org/biomodels.sbo/SBO:0000347"
  R5 hypernym "http://identifiers.org/go/GO:0004872"
  R6 hypernym "http://identifiers.org/go/GO:0004872"
end

MODEL1212040001 is "Smith2009 - RGS mediated GTP hydrolysis"

MODEL1212040001 model_entity_is "http://identifiers.org/biomodels.db/MODEL1212040001"
MODEL1212040001 model_entity_is "http://identifiers.org/biomodels.db/BIOMD0000000439"
MODEL1212040001 description "http://identifiers.org/pubmed/19285552"
MODEL1212040001 origin "http://identifiers.org/pubmed/12446706"
MODEL1212040001 taxon "http://identifiers.org/taxonomy/4896"
MODEL1212040001 parthood "http://identifiers.org/go/GO:0008277"
MODEL1212040001 property "http://identifiers.org/mamo/MAMO_0000046"
