// Created by libAntimony v2.13.0
model *Cooling2007_IP3transients_CardiacMyocyte()

  // Compartments and Species:
  compartment Compartment;
  species $Gd in Compartment, $Gt in Compartment, $R in Compartment, $Rl in Compartment;
  species $Rg in Compartment, $Rlg in Compartment, $Rlgp in Compartment, $IP3 in Compartment;
  species $Pc in Compartment, $Pcg in Compartment, $P in Compartment, $Pg in Compartment;
  species $Ca in Compartment;

  // Assignment Rules:
  J7 := kf7*Gt;
  J13 := kf13*Pg;
  J12 := kf12*Pcg;
  J2 := kf2*R*Gd - kr2*Rg;
  J3 := kf3*Rl*Gd - kr3*Rlg;
  J6 := kf6*Rlg;
  J9 := kf9*P*Gt - kr9*Pg;
  J10 := kf10*Pc*Gt - kr10*Pcg;
  J1 := kf1*R*L - kr1*Rl;
  J4 := kf4*L*Rg - kr4*Rlg;
  J5 := kf5*Rlg;
  Cpc := Cc/Cp;
  J14 := kf14*Pc*PIP2/(Km14/Cpc + PIP2);
  J15 := kf15*Pcg*PIP2/(Km15/Cpc + PIP2);
  J16 := kf16*IP3;
  J8 := kf8*P*Ca - kr8*Pc;
  J11 := kf11*Pg*Ca - kr11*Pcg;
  L := piecewise(Ls/(1 + exp(-80*(time - ts - 0.05))), (time < (ts + 0.15)) && (time >= ts), Ls, time >= (ts + 0.15), 0);
  kr1 := kf1*Kd1;
  kr2 := kf2*Kd2;
  kr4 := kf4*Kd4;
  kr11 := kf11*Kd11;
  Cc := 1/(Vc*602.2);
  Cp := 1/(Vc*Rpc);

  // Rate Rules:
  Gd' = J7 + J13 + J12 - (J2 + J3);
  Gt' = J6 - (J7 + J9 + J10);
  R' = -1*(J1 + J2);
  Rl' = J1 + J6 - J3;
  Rg' = J2 - J4;
  Rlg' = (J3 - J5) + J4 - J6;
  Rlgp' = J5;
  IP3' = Cpc*(J14 + J15) - J16;
  Pc' = J8 + J12 - J10;
  Pcg' = J10 + J11 - J12;
  P' = J13 - (J9 + J8);
  Pg' = J9 - (J11 + J13);
  Ca' = Cpc*-1*(J8 + J11);

  // Species initializations:
  Gd = 10000;
  Gt = 0;
  R = 13.9;
  Rl = 0;
  Rg = 5.06;
  Rlg = 0;
  Rlgp = 0;
  IP3 = 0.015;
  Pc = 9.09;
  Pcg = 0;
  P = 90.9;
  Pg = 0;
  Ca = 0.1;

  // Compartment initializations:
  Compartment = 1;

  // Variable initializations:
  Ls = 0.1;
  ts = 30;
  PIP2 = 4000;
  kf1 = 0.0003;
  Kd1 = 3e-05;
  kf2 = 0.000275;
  Kd2 = 27500;
  kf3 = 1;
  kr3 = 0.001;
  kf4 = 0.3;
  Kd4 = 3e-05;
  kf5 = 0.0004;
  kf6 = 1;
  kf7 = 0.15;
  kf8 = 0.0167;
  kr8 = 0.0167;
  kf9 = 0.0042;
  kr9 = 1;
  kf10 = 0.042;
  kr10 = 1;
  kf11 = 0.0334;
  Kd11 = 0.1;
  kf12 = 6;
  kf13 = 6;
  kf14 = 0.444;
  Km14 = 19.8;
  kf15 = 3.8;
  Km15 = 5;
  kf16 = 1.25;
  Vc = 2550;
  Rpc = 4.61;

  // Other declarations:
  var J7, J13, J12, J2, J3, J6, J9, J10, J1, J4, J5, Cpc, J14, J15, J16, J8;
  var J11, L, kr1, kr2, kr4, kr11, Cc, Cp;
  const Compartment, Ls, ts, PIP2, kf1, Kd1, kf2, Kd2, kf3, kr3, kf4, Kd4;
  const kf5, kf6, kf7, kf8, kr8, kf9, kr9, kf10, kr10, kf11, Kd11, kf12, kf13;
  const kf14, Km14, kf15, Km15, kf16, Vc, Rpc;

  // SBO terms:
  Compartment.sboTerm = 290
  Gd.sboTerm = 296
  Gt.sboTerm = 296
  R.sboTerm = 244
  Rl.sboTerm = 297
  Rg.sboTerm = 296
  Rlg.sboTerm = 296
  Rlgp.sboTerm = 296
  IP3.sboTerm = 252
  Pc.sboTerm = 296
  Pcg.sboTerm = 296
  P.sboTerm = 252
  Pg.sboTerm = 296
  Ca.sboTerm = 247
  Ls.sboTerm = 515
  ts.sboTerm = 9
  PIP2.sboTerm = 196
  kf1.sboTerm = 153
  kr1.sboTerm = 156
  Kd1.sboTerm = 356
  kf2.sboTerm = 153
  kr2.sboTerm = 156
  Kd2.sboTerm = 356
  kf3.sboTerm = 153
  kr3.sboTerm = 156
  kf4.sboTerm = 153
  kr4.sboTerm = 156
  Kd4.sboTerm = 356
  kf5.sboTerm = 153
  kf6.sboTerm = 153
  kf7.sboTerm = 153
  kf8.sboTerm = 153
  kr8.sboTerm = 156
  kf9.sboTerm = 153
  kr9.sboTerm = 156
  kf10.sboTerm = 153
  kr10.sboTerm = 156
  kf11.sboTerm = 153
  kr11.sboTerm = 156
  Kd11.sboTerm = 356
  kf12.sboTerm = 153
  kf13.sboTerm = 153
  kf14.sboTerm = 153
  Km14.sboTerm = 27
  kf15.sboTerm = 153
  Km15.sboTerm = 27
  kf16.sboTerm = 153
  Vc.sboTerm = 468
  Rpc.sboTerm = 468

  // CV terms:
  Compartment identity "http://identifiers.org/go/GO:0005623"
  Gd part "http://identifiers.org/chebi/CHEBI:17552",
          "http://identifiers.org/uniprot/P27600"
  Gt part "http://identifiers.org/chebi/CHEBI:15996",
          "http://identifiers.org/uniprot/P27600"
  R hypernym "http://identifiers.org/uniprot/P35412"
  Rl part "http://identifiers.org/uniprot/P35412",
          "http://identifiers.org/cco/CCO:F0001633"
  Rg part "http://identifiers.org/chebi/CHEBI:17552",
          "http://identifiers.org/uniprot/P35412",
          "http://identifiers.org/uniprot/P27600"
  Rlg part "http://identifiers.org/chebi/CHEBI:17552",
           "http://identifiers.org/uniprot/P35412",
           "http://identifiers.org/uniprot/P27600",
           "http://identifiers.org/cco/CCO:F0001633"
  Rlgp part "http://identifiers.org/chebi/CHEBI:17552",
            "http://identifiers.org/uniprot/P35412",
            "http://identifiers.org/uniprot/P27600",
            "http://identifiers.org/cco/CCO:F0001633"
  Rlgp hypernym "urn:miriam:mod:MOD%3A00696"
  IP3 hypernym "http://identifiers.org/uniprot/Q8R071"
  Pc part "http://identifiers.org/chebi/CHEBI:29108",
          "http://identifiers.org/uniprot/Q9Z1B3"
  Pcg part "http://identifiers.org/chebi/CHEBI:29108",
           "http://identifiers.org/chebi/CHEBI:15996",
           "http://identifiers.org/uniprot/Q9Z1B3",
           "http://identifiers.org/uniprot/P27600"
  P hypernym "http://identifiers.org/uniprot/Q9Z1B3"
  Pg part "http://identifiers.org/chebi/CHEBI:15996",
          "http://identifiers.org/uniprot/Q9Z1B3",
          "http://identifiers.org/uniprot/P27600"
  Ca hypernym "http://identifiers.org/chebi/CHEBI:29108"
end

Cooling2007_IP3transients_CardiacMyocyte is "Cooling2007_IP3transients_CardiacMyocyte"

Cooling2007_IP3transients_CardiacMyocyte model_entity_is "http://identifiers.org/biomodels.db/MODEL0913194523"
Cooling2007_IP3transients_CardiacMyocyte model_entity_is "http://identifiers.org/biomodels.db/BIOMD0000000400"
Cooling2007_IP3transients_CardiacMyocyte description "http://identifiers.org/pubmed/17693463"
Cooling2007_IP3transients_CardiacMyocyte taxon "http://identifiers.org/taxonomy/10090"
Cooling2007_IP3transients_CardiacMyocyte hypernym "http://identifiers.org/fma/FMA:83108"
Cooling2007_IP3transients_CardiacMyocyte hypernym "http://identifiers.org/go/GO:0003300",
                                                  "http://identifiers.org/go/GO:0048016",
                                                  "http://identifiers.org/go/GO:0003015"
Cooling2007_IP3transients_CardiacMyocyte property "http://identifiers.org/mamo/MAMO_0000046"
