// Created by libAntimony v2.13.0
model *Maree2006_DuCa_Type1DiabetesModel()

  // Compartments and Species:
  compartment compartment1;
  species $M in compartment1, $Ma in compartment1, $Ba in compartment1, $Bn in compartment1;
  species $Cy in compartment1;

  // Assignment Rules:
  W := Wmax*exp(-parameter_1);
  parameter_1 := ((time - 9)/3)^2;

  // Rate Rules:
  M' = J + (k + b)*Ma - c*M - f1*M*Ba - e1*M*(M + Ma);
  Ma' = f1*M*Ba - k*Ma - e2*Ma*(M + Ma);
  Ba' = W + Amax*Cy/(kc + Cy) - (f1*M + f2*Ma + d)*Ba;
  Bn' = d*Ba - (f1*M + f2*Ma)*Bn;
  Cy' = alpha*Bn*Ma - delta*Cy;

  // Species initializations:
  M = 477000;
  Ma = 0;
  Ba = 0;
  Bn = 0;
  Cy = 0;

  // Compartment initializations:
  compartment1 = 1;

  // Variable initializations:
  J = 50000;
  k = 0.4;
  b = 0.09;
  c = 0.1;
  f1 = 1e-05;
  e1 = 1e-08;
  e2 = 1e-08;
  d = 0.5;
  f2 = 1e-05;
  Amax = 20000000;
  kc = 1;
  alpha = 5e-09;
  delta = 25;
  g = 1e-05;
  Wmax = 40000000;

  // Other declarations:
  var W, parameter_1;
  const compartment1, J, k, b, c, f1, e1, e2, d, f2, Amax, kc, alpha, delta;
  const g, Wmax;

  // Display Names:
  parameter_1 is "x";

  // SBO terms:
  J.sboTerm = 185
  k.sboTerm = 9
  b.sboTerm = 9
  c.sboTerm = 9
  f1.sboTerm = 9
  e1.sboTerm = 9
  e2.sboTerm = 9
  d.sboTerm = 9
  f2.sboTerm = 9
  W.sboTerm = 9
  Amax.sboTerm = 9
  kc.sboTerm = 9
  alpha.sboTerm = 9
  delta.sboTerm = 9
  g.sboTerm = 9
  Wmax.sboTerm = 9
  parameter_1.sboTerm = 9

  // CV terms:
  M hypernym "http://identifiers.org/bto/BTO:0000801"
  Ma hypernym "http://identifiers.org/bto/BTO:0000801"
  Ba hypernym "http://identifiers.org/bto/BTO:0000783"
  Bn hypernym "http://identifiers.org/bto/BTO:0000783"
end

Maree2006_DuCa_Type1DiabetesModel is "Maree2006_DuCa_Type1DiabetesModel"

Maree2006_DuCa_Type1DiabetesModel model_entity_is "http://identifiers.org/biomodels.db/MODEL1110070000"
Maree2006_DuCa_Type1DiabetesModel model_entity_is "http://identifiers.org/biomodels.db/BIOMD0000000381"
Maree2006_DuCa_Type1DiabetesModel description "http://identifiers.org/pubmed/16608707"
Maree2006_DuCa_Type1DiabetesModel origin "http://identifiers.org/pubmed/10480594"
Maree2006_DuCa_Type1DiabetesModel taxon "http://identifiers.org/taxonomy/10090"
Maree2006_DuCa_Type1DiabetesModel hypernym "http://identifiers.org/go/GO:0071888",
                                           "http://identifiers.org/go/GO:0006909",
                                           "http://identifiers.org/go/GO:0042116"
Maree2006_DuCa_Type1DiabetesModel hypernym "http://identifiers.org/doid/DOID:9744"
