// Created by libAntimony v2.13.0
model *ralser()

  // Compartments and Species:
  compartment extracellular, cytoplasm;
  species P in cytoplasm, G6P in cytoplasm, F6P in cytoplasm, F16P in cytoplasm;
  species NADH in cytoplasm, NAD in cytoplasm, BPG in cytoplasm, P3G in cytoplasm;
  species P2G in cytoplasm, PEP in cytoplasm, PYR in cytoplasm, ACE in cytoplasm;
  species $CO2 in extracellular, $ETOH in extracellular, $SUCC in extracellular;
  species $X in cytoplasm, GA3P in cytoplasm, DHAP in cytoplasm, $GLY in extracellular;
  species D6PGluconoLactone in cytoplasm, D6PGluconate in cytoplasm, NADP in cytoplasm;
  species NADPH in cytoplasm, Ribulose5P in cytoplasm, Ribose5P in cytoplasm;
  species Xyl5P in cytoplasm, Seduhept7P in cytoplasm, Erythrose4P in cytoplasm;
  species $GLCo in extracellular, GLCi in cytoplasm, $F26BP in cytoplasm;

  // Assignment Rules:
  ratio_NADPH_NADP := NADPH/NADP;

  // Reactions:
  vGLK: GLCi + P -> G6P; cytoplasm*(vGLK_VmGLK*(-(G6P*(SUMAXP - ((SUMAXP^2 - 2*SUMAXP*P) + 8*vGLK_KeqAK*SUMAXP*P + P^2 - 4*vGLK_KeqAK*P^2)^0.5)/((1 - 4*vGLK_KeqAK)*vGLK_KeqGLK)) + GLCi*((-SUMAXP + P - 4*vGLK_KeqAK*P) + ((SUMAXP^2 - 2*SUMAXP*P) + 8*vGLK_KeqAK*SUMAXP*P + P^2 - 4*vGLK_KeqAK*P^2)^0.5)/(2 - 8*vGLK_KeqAK))/(vGLK_KmGLKATP*vGLK_KmGLKGLCi*(1 + G6P/vGLK_KmGLKG6P + GLCi/vGLK_KmGLKGLCi)*(1 + (SUMAXP - ((SUMAXP^2 - 2*SUMAXP*P) + 8*vGLK_KeqAK*SUMAXP*P + P^2 - 4*vGLK_KeqAK*P^2)^0.5)/((1 - 4*vGLK_KeqAK)*vGLK_KmGLKADP) + ((-SUMAXP + P - 4*vGLK_KeqAK*P) + ((SUMAXP^2 - 2*SUMAXP*P) + 8*vGLK_KeqAK*SUMAXP*P + P^2 - 4*vGLK_KeqAK*P^2)^0.5)/((2 - 8*vGLK_KeqAK)*vGLK_KmGLKATP))));
  vPGI: G6P -> F6P; cytoplasm*((vPGI_VmPGI/vPGI_KmPGIG6P)*(G6P - F6P/vPGI_KeqPGI)/(1 + G6P/vPGI_KmPGIG6P + F6P/vPGI_KmPGIF6P));
  vPFK: F6P + P -> F16P; cytoplasm*(vPFK_gR*vPFK_VmPFK*F6P*((-SUMAXP + P - 4*vPFK_KeqAK*P) + ((SUMAXP^2 - 2*SUMAXP*P) + 8*vPFK_KeqAK*SUMAXP*P + P^2 - 4*vPFK_KeqAK*P^2)^0.5)*(1 + F6P/vPFK_KmPFKF6P + ((-SUMAXP + P - 4*vPFK_KeqAK*P) + ((SUMAXP^2 - 2*SUMAXP*P) + 8*vPFK_KeqAK*SUMAXP*P + P^2 - 4*vPFK_KeqAK*P^2)^0.5)/((2 - 8*vPFK_KeqAK)*vPFK_KmPFKATP) + vPFK_gR*F6P*((-SUMAXP + P - 4*vPFK_KeqAK*P) + ((SUMAXP^2 - 2*SUMAXP*P) + 8*vPFK_KeqAK*SUMAXP*P + P^2 - 4*vPFK_KeqAK*P^2)^0.5)/((2 - 8*vPFK_KeqAK)*vPFK_KmPFKATP*vPFK_KmPFKF6P))/((2 - 8*vPFK_KeqAK)*vPFK_KmPFKATP*vPFK_KmPFKF6P*(vPFK_L0*(1 + vPFK_CPFKF26BP*F26BP/vPFK_KPFKF26BP + vPFK_CPFKF16BP*F16P/vPFK_KPFKF16BP)^2*(1 + 2*vPFK_CPFKAMP*vPFK_KeqAK*(SUMAXP - ((SUMAXP^2 - 2*SUMAXP*P) + 8*vPFK_KeqAK*SUMAXP*P + P^2 - 4*vPFK_KeqAK*P^2)^0.5)^2/((-1 + 4*vPFK_KeqAK)*vPFK_KPFKAMP*((SUMAXP - P) + 4*vPFK_KeqAK*P - ((SUMAXP^2 - 2*SUMAXP*P) + 8*vPFK_KeqAK*SUMAXP*P + P^2 - 4*vPFK_KeqAK*P^2)^0.5)))^2*(1 + vPFK_CiPFKATP*((-SUMAXP + P - 4*vPFK_KeqAK*P) + ((SUMAXP^2 - 2*SUMAXP*P) + 8*vPFK_KeqAK*SUMAXP*P + P^2 - 4*vPFK_KeqAK*P^2)^0.5)/((2 - 8*vPFK_KeqAK)*vPFK_KiPFKATP))^2*(1 + vPFK_CPFKATP*((-SUMAXP + P - 4*vPFK_KeqAK*P) + ((SUMAXP^2 - 2*SUMAXP*P) + 8*vPFK_KeqAK*SUMAXP*P + P^2 - 4*vPFK_KeqAK*P^2)^0.5)/((2 - 8*vPFK_KeqAK)*vPFK_KmPFKATP))^2/((1 + F26BP/vPFK_KPFKF26BP + F16P/vPFK_KPFKF16BP)^2*(1 + 2*vPFK_KeqAK*(SUMAXP - ((SUMAXP^2 - 2*SUMAXP*P) + 8*vPFK_KeqAK*SUMAXP*P + P^2 - 4*vPFK_KeqAK*P^2)^0.5)^2/((-1 + 4*vPFK_KeqAK)*vPFK_KPFKAMP*((SUMAXP - P) + 4*vPFK_KeqAK*P - ((SUMAXP^2 - 2*SUMAXP*P) + 8*vPFK_KeqAK*SUMAXP*P + P^2 - 4*vPFK_KeqAK*P^2)^0.5)))^2*(1 + ((-SUMAXP + P - 4*vPFK_KeqAK*P) + ((SUMAXP^2 - 2*SUMAXP*P) + 8*vPFK_KeqAK*SUMAXP*P + P^2 - 4*vPFK_KeqAK*P^2)^0.5)/((2 - 8*vPFK_KeqAK)*vPFK_KiPFKATP))^2) + (1 + F6P/vPFK_KmPFKF6P + ((-SUMAXP + P - 4*vPFK_KeqAK*P) + ((SUMAXP^2 - 2*SUMAXP*P) + 8*vPFK_KeqAK*SUMAXP*P + P^2 - 4*vPFK_KeqAK*P^2)^0.5)/((2 - 8*vPFK_KeqAK)*vPFK_KmPFKATP) + vPFK_gR*F6P*((-SUMAXP + P - 4*vPFK_KeqAK*P) + ((SUMAXP^2 - 2*SUMAXP*P) + 8*vPFK_KeqAK*SUMAXP*P + P^2 - 4*vPFK_KeqAK*P^2)^0.5)/((2 - 8*vPFK_KeqAK)*vPFK_KmPFKATP*vPFK_KmPFKF6P))^2)));
  vALD: F16P -> DHAP + GA3P; cytoplasm*((vALD_VmALD*F16P/vALD_KmALDF16P)*(1 - DHAP*GA3P/(F16P*vALD_KeqALD))/(1 + F16P/vALD_KmALDF16P + DHAP/vALD_KmALDDHAP + GA3P/vALD_KmALDGAP + F16P*GA3P/(vALD_KmALDF16P*vALD_KmALDGAPi) + DHAP*GA3P/(vALD_KmALDDHAP*vALD_KmALDGAP)));
  vG3PDH: DHAP + NADH -> $GLY + NAD; cytoplasm*(vG3PDH_VmG3PDH*(-(GLY*NAD/vG3PDH_KeqG3PDH) + NADH*DHAP/(1 + vG3PDH_KeqTPI))/(vG3PDH_KmG3PDHDHAP*vG3PDH_KmG3PDHNADH*(1 + NAD/vG3PDH_KmG3PDHNAD + NADH/vG3PDH_KmG3PDHNADH)*(1 + GLY/vG3PDH_KmG3PDHGLY + DHAP/((1 + vG3PDH_KeqTPI)*vG3PDH_KmG3PDHDHAP))));
  vGAPDH: GA3P + NAD -> BPG + NADH; cytoplasm*((k_rel_GAPDH*vGAPDH_VmGAPDHf*GA3P*NAD/(vGAPDH_KmGAPDHGAP*vGAPDH_KmGAPDHNAD))*(1 - BPG*NADH/(GA3P*NAD*vGAPDH_KeqGAPDH))/((1 + GA3P/vGAPDH_KmGAPDHGAP + BPG/vGAPDH_KmGAPDHBPG)*(1 + NAD/vGAPDH_KmGAPDHNAD + NADH/vGAPDH_KmGAPDHNADH)));
  vPGK: BPG -> P3G + P; cytoplasm*(vPGK_VmPGK*(vPGK_KeqPGK*BPG*(SUMAXP - ((SUMAXP^2 - 2*SUMAXP*P) + 8*vPGK_KeqAK*SUMAXP*P + P^2 - 4*vPGK_KeqAK*P^2)^0.5)/(1 - 4*vPGK_KeqAK) - ((-SUMAXP + P - 4*vPGK_KeqAK*P) + ((SUMAXP^2 - 2*SUMAXP*P) + 8*vPGK_KeqAK*SUMAXP*P + P^2 - 4*vPGK_KeqAK*P^2)^0.5)*P3G/(2 - 8*vPGK_KeqAK))/(vPGK_KmPGKATP*vPGK_KmPGKP3G*(1 + (SUMAXP - ((SUMAXP^2 - 2*SUMAXP*P) + 8*vPGK_KeqAK*SUMAXP*P + P^2 - 4*vPGK_KeqAK*P^2)^0.5)/((1 - 4*vPGK_KeqAK)*vPGK_KmPGKADP) + ((-SUMAXP + P - 4*vPGK_KeqAK*P) + ((SUMAXP^2 - 2*SUMAXP*P) + 8*vPGK_KeqAK*SUMAXP*P + P^2 - 4*vPGK_KeqAK*P^2)^0.5)/((2 - 8*vPGK_KeqAK)*vPGK_KmPGKATP))*(1 + BPG/vPGK_KmPGKBPG + P3G/vPGK_KmPGKP3G)));
  vPGM: P3G -> P2G; cytoplasm*((vPGM_VmPGM/vPGM_KmPGMP3G)*(P3G - P2G/vPGM_KeqPGM)/(1 + P3G/vPGM_KmPGMP3G + P2G/vPGM_KmPGMP2G));
  vENO: P2G -> PEP; cytoplasm*((vENO_VmENO/vENO_KmENOP2G)*(P2G - PEP/vENO_KeqENO)/(1 + P2G/vENO_KmENOP2G + PEP/vENO_KmENOPEP));
  vPYK: PEP -> PYR + P; cytoplasm*((vPYK_VmPYK/(vPYK_KmPYKPEP*vPYK_KmPYKADP))*(PEP*(SUMAXP - ((P^2 - 4*vPYK_KeqAK*P^2 - 2*P*SUMAXP) + 8*vPYK_KeqAK*P*SUMAXP + SUMAXP^2)^0.5)/(1 - 4*vPYK_KeqAK) - PYR*((P - 4*vPYK_KeqAK*P - SUMAXP) + ((P^2 - 4*vPYK_KeqAK*P^2 - 2*P*SUMAXP) + 8*vPYK_KeqAK*P*SUMAXP + SUMAXP^2)^0.5)/(2 - 8*vPYK_KeqAK)/vPYK_KeqPYK)/((1 + PEP/vPYK_KmPYKPEP + PYR/vPYK_KmPYKPYR)*(1 + ((P - 4*vPYK_KeqAK*P - SUMAXP) + ((P^2 - 4*vPYK_KeqAK*P^2 - 2*P*SUMAXP) + 8*vPYK_KeqAK*P*SUMAXP + SUMAXP^2)^0.5)/(2 - 8*vPYK_KeqAK)/vPYK_KmPYKATP + (SUMAXP - ((P^2 - 4*vPYK_KeqAK*P^2 - 2*P*SUMAXP) + 8*vPYK_KeqAK*P*SUMAXP + SUMAXP^2)^0.5)/(1 - 4*vPYK_KeqAK)/vPYK_KmPYKADP)));
  vPDC: PYR -> ACE + $CO2; cytoplasm*(vPDC_VmPDC*PYR^vPDC_nPDC/vPDC_KmPDCPYR^vPDC_nPDC/(1 + PYR^vPDC_nPDC/vPDC_KmPDCPYR^vPDC_nPDC));
  vSUC: 2 ACE + 3 NAD -> 3 NADH + $SUCC; cytoplasm*vSUC_KSUCC*ACE;
  vADH: ACE + NADH -> $ETOH + NAD; cytoplasm*-((vADH_VmADH/(vADH_KiADHNAD*vADH_KmADHETOH))*(NAD*ETOH - NADH*ACE/vADH_KeqADH)/(1 + NAD/vADH_KiADHNAD + vADH_KmADHNAD*ETOH/(vADH_KiADHNAD*vADH_KmADHETOH) + vADH_KmADHNADH*ACE/(vADH_KiADHNADH*vADH_KmADHACE) + NADH/vADH_KiADHNADH + NAD*ETOH/(vADH_KiADHNAD*vADH_KmADHETOH) + vADH_KmADHNADH*NAD*ACE/(vADH_KiADHNAD*vADH_KiADHNADH*vADH_KmADHACE) + vADH_KmADHNAD*ETOH*NADH/(vADH_KiADHNAD*vADH_KmADHETOH*vADH_KiADHNADH) + NADH*ACE/(vADH_KiADHNADH*vADH_KmADHACE) + NAD*ETOH*ACE/(vADH_KiADHNAD*vADH_KmADHETOH*vADH_KiADHACE) + ETOH*NADH*ACE/(vADH_KiADHETOH*vADH_KiADHNADH*vADH_KmADHACE)));
  vATP: P -> $X; cytoplasm*(vATP_KATPASE*((P - 4*vATP_KeqAK*P - SUMAXP) + ((P^2 - 4*vATP_KeqAK*P^2 - 2*P*SUMAXP) + 8*vATP_KeqAK*P*SUMAXP + SUMAXP^2)^0.5)/(2 - 8*vATP_KeqAK));
  vTPI: GA3P -> DHAP; cytoplasm*(k_rel_TPI*(vTPI_VmDHAP*GA3P/vTPI_KmGA3P - vTPI_VmGA3P*DHAP/vTPI_KmDHAP)/(1 + GA3P/vTPI_KmGA3P + DHAP/vTPI_KmDHAP));
  vG6PDH: G6P + NADP => D6PGluconoLactone + NADPH; cytoplasm*(vG6PDH_VmG6PDH*G6P*NADP/(vG6PDH_KmG6P*vG6PDH_KmNADP)/((1 + G6P/vG6PDH_KmG6P + NADPH/vG6PDH_KiNADPH)*(1 + NADP/vG6PDH_KmNADP)));
  v6PGL: D6PGluconoLactone => D6PGluconate; cytoplasm*(v6PGL_Vm6PGL*D6PGluconoLactone/(v6PGL_Km6PGL + D6PGluconoLactone));
  vGluDH: D6PGluconate + NADP => Ribulose5P + NADPH; cytoplasm*(vGluDH_VmGluDH*D6PGluconate*NADP/(vGluDH_KmGluconate*vGluDH_KmNADP)/((1 + D6PGluconate/vGluDH_KmGluconate + NADPH/vGluDH_KiNADPH)*(1 + NADP/vGluDH_KmNADP)));
  vPPI: Ribulose5P -> Ribose5P; cytoplasm*((vPPI_VmPPIf*Ribulose5P/vPPI_KmRibu5P - vPPI_VmPPIr*Ribose5P/vPPI_KmRibo5P)/(1 + Ribulose5P/vPPI_KmRibu5P + Ribose5P/vPPI_KmRibo5P));
  vTransk1: Ribose5P + Xyl5P -> GA3P + Seduhept7P; cytoplasm*((vTransk1_VmTransk1f*Ribose5P*Xyl5P/(vTransk1_KmRibose5P*vTransk1_KmXyl5P) - vTransk1_VmTransk1r*GA3P*Seduhept7P/(vTransk1_KmGA3P*vTransk1_KmSeduhept))/((1 + Ribose5P/vTransk1_KmRibose5P + GA3P/vTransk1_KmGA3P)*(1 + Xyl5P/vTransk1_KmXyl5P + Seduhept7P/vTransk1_KmSeduhept)));
  vR5PI: Ribulose5P -> Xyl5P; cytoplasm*((vR5PI_VmR5PIf*Ribulose5P/vR5PI_KmRibu5P - vR5PI_VmR5PIr*Xyl5P/vR5PI_KmXyl)/(1 + Ribulose5P/vR5PI_KmRibu5P + Xyl5P/vR5PI_KmXyl));
  vTransald: Seduhept7P + GA3P -> F6P + Erythrose4P; cytoplasm*((vTransald_VmTransaldf*GA3P*Seduhept7P/(vTransald_KmGA3P*vTransald_KmSeduhept) - vTransald_VmTransaldr*F6P*Erythrose4P/(vTransald_KmF6P*vTransald_KmEry4P))/((1 + GA3P/vTransald_KmGA3P + F6P/vTransald_KmF6P)*(1 + Seduhept7P/vTransald_KmSeduhept + Erythrose4P/vTransald_KmEry4P)));
  vTransk2: Xyl5P + Erythrose4P -> GA3P + F6P; cytoplasm*((vTransk2_VmTransk2f*Erythrose4P*Xyl5P/(vTransk2_KmEry4P*vTransk2_KmXyl5P) - vTransk2_VmTransk2r*F6P*GA3P/(vTransk2_KmF6P*vTransk2_KmGA3P))/((1 + Xyl5P/vTransk2_KmXyl5P + GA3P/vTransk2_KmGA3P)*(1 + Erythrose4P/vTransk2_KmEry4P + F6P/vTransk2_KmF6P)));
  vNADPH: NADPH => NADP; cytoplasm*vNADPH_kNADPH*NADPH;
  vGLT: $GLCo -> GLCi; cytoplasm*(vGLT_VmGLT*(GLCo - GLCi/vGLT_KeqGLT)/(vGLT_KmGLTGLCo*(1 + GLCo/vGLT_KmGLTGLCo + GLCi/vGLT_KmGLTGLCi + 0.91*GLCo*GLCi/(vGLT_KmGLTGLCi*vGLT_KmGLTGLCo))));

  // Species initializations:
  P = 5;
  G6P = 1.39;
  F6P = 0.28;
  F16P = 0.1;
  NADH = 0.39;
  NAD = 1.2;
  BPG = 0.1;
  P3G = 0.1;
  P2G = 0.1;
  PEP = 0.1;
  PYR = 3.36;
  ACE = 0.04;
  CO2 = 1;
  ETOH = 50;
  SUCC = 0.1;
  X = 0.1;
  GA3P = 0.05;
  DHAP = 1;
  GLY = 0.15;
  D6PGluconoLactone = 0.1;
  D6PGluconate = 0.1;
  NADP = 0.4;
  NADPH = 1.6;
  Ribulose5P = 0.1;
  Ribose5P = 0.1;
  Xyl5P = 0.1;
  Seduhept7P = 0.1;
  Erythrose4P = 0;
  GLCo = 50;
  GLCi = 0.087;
  F26BP = 0.02;

  // Compartment initializations:
  extracellular = 1;
  cytoplasm = 1;

  // Variable initializations:
  k_rel_TPI = 1;
  k_rel_TPI has dimensionless;
  k_rel_GAPDH = 1;
  k_rel_GAPDH has dimensionless;
  ratio_NADPH_NADP has dimensionless;
  SUMAXP = 4.1;
  vGLK_VmGLK = 226.452;
  vGLK_VmGLK has mMpermin;
  vGLK_KeqAK = 0.45;
  vGLK_KeqAK has dimensionless;
  vGLK_KeqGLK = 3800;
  vGLK_KeqGLK has dimensionless;
  vGLK_KmGLKATP = 0.15;
  vGLK_KmGLKATP has mM;
  vGLK_KmGLKGLCi = 0.08;
  vGLK_KmGLKGLCi has mM;
  vGLK_KmGLKG6P = 30;
  vGLK_KmGLKG6P has mM;
  vGLK_KmGLKADP = 0.23;
  vGLK_KmGLKADP has mM;
  vPGI_VmPGI = 339.677;
  vPGI_VmPGI has mMpermin;
  vPGI_KmPGIG6P = 1.4;
  vPGI_KmPGIG6P has mM;
  vPGI_KeqPGI = 0.314;
  vPGI_KeqPGI has dimensionless;
  vPGI_KmPGIF6P = 0.3;
  vPGI_KmPGIF6P has mM;
  vPFK_gR = 5.12;
  vPFK_gR has dimensionless;
  vPFK_VmPFK = 182.903;
  vPFK_VmPFK has mMpermin;
  vPFK_KeqAK = 0.45;
  vPFK_KeqAK has dimensionless;
  vPFK_KmPFKF6P = 0.1;
  vPFK_KmPFKF6P has mM;
  vPFK_KmPFKATP = 0.71;
  vPFK_KmPFKATP has mM;
  vPFK_L0 = 0.66;
  vPFK_L0 has dimensionless;
  vPFK_CPFKF26BP = 0.0174;
  vPFK_CPFKF26BP has dimensionless;
  vPFK_KPFKF26BP = 0.000682;
  vPFK_KPFKF26BP has mM;
  vPFK_CPFKF16BP = 0.397;
  vPFK_CPFKF16BP has dimensionless;
  vPFK_KPFKF16BP = 0.111;
  vPFK_KPFKF16BP has mM;
  vPFK_CPFKAMP = 0.0845;
  vPFK_CPFKAMP has dimensionless;
  vPFK_KPFKAMP = 0.0995;
  vPFK_KPFKAMP has mM;
  vPFK_CiPFKATP = 100;
  vPFK_CiPFKATP has dimensionless;
  vPFK_KiPFKATP = 0.65;
  vPFK_KiPFKATP has mM;
  vPFK_CPFKATP = 3;
  vPFK_CPFKATP has dimensionless;
  vALD_VmALD = 322.258;
  vALD_VmALD has mMpermin;
  vALD_KeqTPI = 0.045;
  vALD_KeqTPI has dimensionless;
  vALD_KeqALD = 0.069;
  vALD_KeqALD has dimensionless;
  vALD_KmALDF16P = 0.3;
  vALD_KmALDF16P has mM;
  vALD_KmALDDHAP = 2.4;
  vALD_KmALDDHAP has mM;
  vALD_KmALDGAP = 2;
  vALD_KmALDGAP has mM;
  vALD_KmALDGAPi = 10;
  vALD_KmALDGAPi has mM;
  vG3PDH_VmG3PDH = 70.15;
  vG3PDH_VmG3PDH has mMpermin;
  vG3PDH_KeqG3PDH = 4300;
  vG3PDH_KeqG3PDH has dimensionless;
  vG3PDH_KeqTPI = 0.045;
  vG3PDH_KeqTPI has dimensionless;
  vG3PDH_KmG3PDHDHAP = 0.4;
  vG3PDH_KmG3PDHDHAP has mM;
  vG3PDH_KmG3PDHNADH = 0.023;
  vG3PDH_KmG3PDHNADH has mM;
  vG3PDH_KmG3PDHNAD = 0.93;
  vG3PDH_KmG3PDHNAD has mM;
  vG3PDH_KmG3PDHGLY = 1;
  vG3PDH_KmG3PDHGLY has mM;
  vGAPDH_VmGAPDHr = 6549.68;
  vGAPDH_VmGAPDHr has mMpermin;
  vGAPDH_KmGAPDHBPG = 0.0098;
  vGAPDH_KmGAPDHBPG has mM;
  vGAPDH_KmGAPDHNADH = 0.06;
  vGAPDH_KmGAPDHNADH has mM;
  vGAPDH_KeqTPI = 0.045;
  vGAPDH_KeqTPI has dimensionless;
  vGAPDH_VmGAPDHf = 1184.52;
  vGAPDH_VmGAPDHf has mMpermin;
  vGAPDH_KmGAPDHGAP = 0.21;
  vGAPDH_KmGAPDHGAP has mM;
  vGAPDH_KmGAPDHNAD = 0.09;
  vGAPDH_KmGAPDHNAD has mM;
  vGAPDH_KeqGAPDH = 0.005;
  vGAPDH_KeqGAPDH has dimensionless;
  vPGK_VmPGK = 1306.45;
  vPGK_VmPGK has mMpermin;
  vPGK_KeqPGK = 3200;
  vPGK_KeqPGK has dimensionless;
  vPGK_KeqAK = 0.45;
  vPGK_KeqAK has dimensionless;
  vPGK_KmPGKATP = 0.3;
  vPGK_KmPGKATP has mM;
  vPGK_KmPGKP3G = 0.53;
  vPGK_KmPGKP3G has mM;
  vPGK_KmPGKADP = 0.2;
  vPGK_KmPGKADP has mM;
  vPGK_KmPGKBPG = 0.003;
  vPGK_KmPGKBPG has mM;
  vPGM_VmPGM = 2525.81;
  vPGM_VmPGM has mMpermin;
  vPGM_KmPGMP3G = 1.2;
  vPGM_KmPGMP3G has mM;
  vPGM_KeqPGM = 0.19;
  vPGM_KeqPGM has dimensionless;
  vPGM_KmPGMP2G = 0.08;
  vPGM_KmPGMP2G has mM;
  vENO_VmENO = 365.806;
  vENO_VmENO has mMpermin;
  vENO_KmENOP2G = 0.04;
  vENO_KmENOP2G has mM;
  vENO_KeqENO = 6.7;
  vENO_KeqENO has dimensionless;
  vENO_KmENOPEP = 0.5;
  vENO_KmENOPEP has mM;
  vPYK_VmPYK = 1088.71;
  vPYK_VmPYK has mMpermin;
  vPYK_KmPYKPEP = 0.14;
  vPYK_KmPYKPEP has mM;
  vPYK_KmPYKADP = 0.53;
  vPYK_KmPYKADP has mM;
  vPYK_KeqAK = 0.45;
  vPYK_KeqAK has dimensionless;
  vPYK_KeqPYK = 6500;
  vPYK_KeqPYK has dimensionless;
  vPYK_KmPYKPYR = 21;
  vPYK_KmPYKPYR has mM;
  vPYK_KmPYKATP = 1.5;
  vPYK_KmPYKATP has mM;
  vPDC_VmPDC = 174.194;
  vPDC_VmPDC has mMpermin;
  vPDC_nPDC = 1.9;
  vPDC_nPDC has dimensionless;
  vPDC_KmPDCPYR = 4.33;
  vPDC_KmPDCPYR has mM;
  vSUC_KSUCC = 21.4;
  vSUC_KSUCC has permin;
  vADH_VmADH = 810;
  vADH_VmADH has mMpermin;
  vADH_KiADHNAD = 0.92;
  vADH_KiADHNAD has mM;
  vADH_KmADHETOH = 17;
  vADH_KmADHETOH has mM;
  vADH_KeqADH = 6.9e-05;
  vADH_KeqADH has dimensionless;
  vADH_KmADHNAD = 0.17;
  vADH_KmADHNAD has mM;
  vADH_KmADHNADH = 0.11;
  vADH_KmADHNADH has mM;
  vADH_KiADHNADH = 0.031;
  vADH_KiADHNADH has mM;
  vADH_KmADHACE = 1.11;
  vADH_KmADHACE has mM;
  vADH_KiADHACE = 1.1;
  vADH_KiADHACE has mM;
  vADH_KiADHETOH = 90;
  vADH_KiADHETOH has mM;
  vATP_KATPASE = 39.5;
  vATP_KATPASE has permin;
  vATP_KeqAK = 0.45;
  vATP_KeqAK has dimensionless;
  vTPI_KmGA3P = 1.27;
  vTPI_KmGA3P has mM;
  vTPI_KmDHAP = 1.23;
  vTPI_KmDHAP has mM;
  vTPI_VmDHAP = 10900;
  vTPI_VmDHAP has mMpermin;
  vTPI_VmGA3P = 555;
  vTPI_VmGA3P has mMpermin;
  vG6PDH_VmG6PDH = 4;
  vG6PDH_VmG6PDH has mMpermin;
  vG6PDH_KmG6P = 0.04;
  vG6PDH_KmG6P has mM;
  vG6PDH_KmNADP = 0.02;
  vG6PDH_KmNADP has mM;
  vG6PDH_KiNADPH = 0.017;
  vG6PDH_KiNADPH has mM;
  v6PGL_Vm6PGL = 4;
  v6PGL_Vm6PGL has mMpermin;
  v6PGL_Km6PGL = 0.8;
  v6PGL_Km6PGL has mM;
  vGluDH_VmGluDH = 4;
  vGluDH_VmGluDH has mMpermin;
  vGluDH_KmGluconate = 0.02;
  vGluDH_KmGluconate has mM;
  vGluDH_KmNADP = 0.03;
  vGluDH_KmNADP has mM;
  vGluDH_KiNADPH = 0.03;
  vGluDH_KiNADPH has mM;
  vPPI_VmPPIf = 3458;
  vPPI_VmPPIf has mMpermin;
  vPPI_VmPPIr = 3458;
  vPPI_VmPPIr has mMpermin;
  vPPI_KmRibu5P = 1.6;
  vPPI_KmRibu5P has mM;
  vPPI_KmRibo5P = 1.6;
  vPPI_KmRibo5P has mM;
  vTransk1_VmTransk1f = 4;
  vTransk1_VmTransk1f has mMpermin;
  vTransk1_VmTransk1r = 2;
  vTransk1_VmTransk1r has mMpermin;
  vTransk1_KmRibose5P = 0.1;
  vTransk1_KmRibose5P has mM;
  vTransk1_KmXyl5P = 0.15;
  vTransk1_KmXyl5P has mM;
  vTransk1_KmGA3P = 0.1;
  vTransk1_KmGA3P has mM;
  vTransk1_KmSeduhept = 0.15;
  vTransk1_KmSeduhept has mM;
  vR5PI_VmR5PIf = 1039;
  vR5PI_VmR5PIf has mMpermin;
  vR5PI_VmR5PIr = 1039;
  vR5PI_VmR5PIr has mMpermin;
  vR5PI_KmRibu5P = 1.5;
  vR5PI_KmRibu5P has mM;
  vR5PI_KmXyl = 1.5;
  vR5PI_KmXyl has mM;
  vTransald_VmTransaldf = 55;
  vTransald_VmTransaldf has mMpermin;
  vTransald_VmTransaldr = 10;
  vTransald_VmTransaldr has mMpermin;
  vTransald_KmGA3P = 0.22;
  vTransald_KmGA3P has mM;
  vTransald_KmSeduhept = 0.18;
  vTransald_KmSeduhept has mM;
  vTransald_KmF6P = 0.32;
  vTransald_KmF6P has mM;
  vTransald_KmEry4P = 0.018;
  vTransald_KmEry4P has mM;
  vTransk2_VmTransk2f = 3.2;
  vTransk2_VmTransk2f has mMpermin;
  vTransk2_VmTransk2r = 43;
  vTransk2_VmTransk2r has mMpermin;
  vTransk2_KmXyl5P = 0.16;
  vTransk2_KmXyl5P has mM;
  vTransk2_KmEry4P = 0.09;
  vTransk2_KmEry4P has mM;
  vTransk2_KmF6P = 1.1;
  vTransk2_KmF6P has mM;
  vTransk2_KmGA3P = 2.1;
  vTransk2_KmGA3P has mM;
  vNADPH_kNADPH = 2;
  vNADPH_kNADPH has permin;
  vGLT_VmGLT = 97.264;
  vGLT_VmGLT has mMpermin;
  vGLT_KeqGLT = 1;
  vGLT_KeqGLT has mM;
  vGLT_KmGLTGLCo = 1.1918;
  vGLT_KmGLTGLCo has mM;
  vGLT_KmGLTGLCi = 1.1918;
  vGLT_KmGLTGLCi has mM;

  // Other declarations:
  var ratio_NADPH_NADP;
  const extracellular, cytoplasm, k_rel_TPI, k_rel_GAPDH, SUMAXP;

  // Unit definitions:
  unit substance = 1e-3 mole;
  unit time_unit = 60 second;
  unit mMpermin = 1e-3 mole / (litre * 60 second);
  unit mM = 1e-3 mole / litre;
  unit permin = 1 / 60 second;

  // Display Names:
  substance is "millimole";
  time_unit is "minute";
  P is "High energy phosphates";
  G6P is "Glucose 6 Phosphate";
  F6P is "Fructose 6 Phosphate";
  F16P is "Fructose-1,6 bisphosphate";
  BPG is "1,3-bisphosphoglycerate";
  P3G is "3-phosphoglycerate";
  P2G is "2-phosphoglycerate";
  PEP is "Phosphoenolpyruvate";
  PYR is "Pyruvate";
  ACE is "Acetaldehyde";
  ETOH is "Ethanol";
  SUCC is "Succinate";
  GA3P is "glyceraldehyde 3-phosphate";
  DHAP is "dihydroxyacetone phosphate";
  GLY is "Glycerol";
  D6PGluconoLactone is "D-6-phosphoglucono-delta-lactone";
  D6PGluconate is "6-phosphogluconate";
  NADP is "NADP+";
  Ribulose5P is "ribulose 5-phosphate";
  Ribose5P is "ribose 5-phosphate";
  Xyl5P is "xylulose 5-phosphate";
  Seduhept7P is "sedoheptulose 7-phosphate";
  Erythrose4P is "erythrose 4-phosphate";
  GLCo is "Extracellular Glucose";
  GLCi is "Glucose in Cytosol";
  F26BP is "F2,6P";
  SUMAXP is "sum of AXP conc";
  vGLK is "Hexokinase";
  vPGI is "Glucose-6-phosphate isomerase";
  vPFK is "Phosphofructokinase";
  vALD is "Aldolase";
  vG3PDH is "Glycerol 3-phosphate dehydrogenase";
  vGAPDH is "Glyceraldehyde 3-phosphate dehydrogenase";
  vPGK is "Phosphoglycerate kinase";
  vPGM is "Phosphoglycerate mutase";
  vENO is "Enolase";
  vPYK is "Pyruvate kinase";
  vPDC is "Pyruvate decarboxylase";
  vSUC is "Succinate synthesis";
  vADH is "Alcohol dehydrogenase";
  vATP is "ATPase activity";
  vGLT is "Glucose transport";

  // SBO terms:
  extracellular.sboTerm = 290
  P.sboTerm = 247
  G6P.sboTerm = 247
  F6P.sboTerm = 247
  F16P.sboTerm = 247
  NADH.sboTerm = 247
  NAD.sboTerm = 247
  BPG.sboTerm = 247
  P3G.sboTerm = 247
  P2G.sboTerm = 247
  PEP.sboTerm = 247
  PYR.sboTerm = 247
  ACE.sboTerm = 247
  CO2.sboTerm = 247
  ETOH.sboTerm = 247
  SUCC.sboTerm = 247
  X.sboTerm = 291
  GA3P.sboTerm = 247
  DHAP.sboTerm = 247
  GLY.sboTerm = 247
  D6PGluconoLactone.sboTerm = 247
  D6PGluconate.sboTerm = 247
  NADP.sboTerm = 247
  NADPH.sboTerm = 247
  Ribulose5P.sboTerm = 247
  Ribose5P.sboTerm = 247
  Xyl5P.sboTerm = 247
  Seduhept7P.sboTerm = 247
  Erythrose4P.sboTerm = 247
  GLCo.sboTerm = 247
  GLCi.sboTerm = 247
  F26BP.sboTerm = 247
  vGLK.sboTerm = 216
  vPGI.sboTerm = 377
  vPFK.sboTerm = 216
  vALD.sboTerm = 182
  vG3PDH.sboTerm = 200
  vGAPDH.sboTerm = 200
  vPGK.sboTerm = 216
  vPGM.sboTerm = 377
  vENO.sboTerm = 211
  vPYK.sboTerm = 216
  vPDC.sboTerm = 399
  vSUC.sboTerm = 205
  vADH.sboTerm = 200
  vATP.sboTerm = 376
  vTPI.sboTerm = 377
  vG6PDH.sboTerm = 200
  v6PGL.sboTerm = 376
  vGluDH.sboTerm = 200
  vPPI.sboTerm = 377
  vTransk1.sboTerm = 182
  vR5PI.sboTerm = 377
  vTransald.sboTerm = 182
  vTransk2.sboTerm = 182
  vNADPH.sboTerm = 201
  vGLT.sboTerm = 185

  // CV terms:
  extracellular identity "http://identifiers.org/go/GO:0005576"
  cytoplasm identity "http://identifiers.org/go/GO:0005829"
  P part "http://identifiers.org/kegg.compound/C00008",
         "http://identifiers.org/kegg.compound/C00002",
         "http://identifiers.org/chebi/CHEBI:16761"
  P part "http://identifiers.org/chebi/CHEBI:16761",
         "http://identifiers.org/chebi/CHEBI:15422"
  G6P identity "http://identifiers.org/chebi/CHEBI:17665",
               "http://identifiers.org/kegg.compound/C00668"
  F6P identity "http://identifiers.org/chebi/CHEBI:15946",
               "http://identifiers.org/kegg.compound/C05345"
  F16P identity "http://identifiers.org/chebi/CHEBI:16905",
                "http://identifiers.org/kegg.compound/C00354"
  NADH identity "http://identifiers.org/chebi/CHEBI:16908",
                "http://identifiers.org/kegg.compound/C00004"
  NAD identity "http://identifiers.org/chebi/CHEBI:15846",
               "http://identifiers.org/kegg.compound/C00003"
  BPG identity "http://identifiers.org/chebi/CHEBI:16001",
               "http://identifiers.org/kegg.compound/C00236"
  P3G identity "http://identifiers.org/chebi/CHEBI:17794",
               "http://identifiers.org/kegg.compound/C00197"
  P2G identity "http://identifiers.org/chebi/CHEBI:17835",
               "http://identifiers.org/kegg.compound/C00631"
  PEP identity "http://identifiers.org/chebi/CHEBI:18021",
               "http://identifiers.org/kegg.compound/C00074"
  PYR identity "http://identifiers.org/chebi/CHEBI:15361",
               "http://identifiers.org/kegg.compound/C00022"
  ACE identity "http://identifiers.org/chebi/CHEBI:15343",
               "http://identifiers.org/kegg.compound/C00084"
  CO2 identity "http://identifiers.org/chebi/CHEBI:16526",
               "http://identifiers.org/kegg.compound/C00011"
  ETOH identity "http://identifiers.org/chebi/CHEBI:16236",
                "http://identifiers.org/kegg.compound/C00469"
  SUCC identity "http://identifiers.org/chebi/CHEBI:30031"
  GA3P identity "http://identifiers.org/chebi/CHEBI:17138"
  DHAP identity "http://identifiers.org/chebi/CHEBI:16108"
  GLY identity "http://identifiers.org/chebi/CHEBI:17754",
               "http://identifiers.org/kegg.compound/C00116"
  D6PGluconoLactone identity "http://identifiers.org/chebi/CHEBI:16938"
  D6PGluconate identity "http://identifiers.org/chebi/CHEBI:16863"
  NADP identity "http://identifiers.org/chebi/CHEBI:18009"
  NADPH identity "http://identifiers.org/chebi/CHEBI:16474"
  Ribulose5P identity "http://identifiers.org/chebi/CHEBI:17363"
  Ribose5P identity "http://identifiers.org/chebi/CHEBI:17797"
  Xyl5P identity "http://identifiers.org/chebi/CHEBI:16332"
  Seduhept7P identity "http://identifiers.org/chebi/CHEBI:15721"
  Erythrose4P identity "http://identifiers.org/chebi/CHEBI:48153"
  GLCo identity "http://identifiers.org/chebi/CHEBI:17234",
                "http://identifiers.org/kegg.compound/C00293"
  GLCi identity "http://identifiers.org/chebi/CHEBI:17234",
                "http://identifiers.org/kegg.compound/C00293"
  F26BP identity "http://identifiers.org/chebi/CHEBI:28602",
                 "http://identifiers.org/kegg.compound/C00665"
  SUMAXP part "http://identifiers.org/kegg.compound/C00020",
              "http://identifiers.org/kegg.compound/C00008",
              "http://identifiers.org/kegg.compound/C00002"
  SUMAXP part "http://identifiers.org/chebi/CHEBI:16027",
              "http://identifiers.org/chebi/CHEBI:16761",
              "http://identifiers.org/chebi/CHEBI:15422"
  vGLK homolog "http://identifiers.org/reactome/REACT_1318"
  vGLK identity "http://identifiers.org/ec-code/2.7.1.2",
                "http://identifiers.org/kegg.reaction/R00299"
  vPGI homolog "http://identifiers.org/reactome/REACT_116"
  vPGI identity "http://identifiers.org/ec-code/5.3.1.9",
                "http://identifiers.org/kegg.reaction/R00771"
  vPFK homolog "http://identifiers.org/reactome/REACT_736"
  vPFK identity "http://identifiers.org/ec-code/2.7.1.11",
                "http://identifiers.org/kegg.reaction/R00756"
  vALD homolog "http://identifiers.org/reactome/REACT_1602"
  vALD identity "http://identifiers.org/ec-code/4.1.2.13",
                "http://identifiers.org/kegg.reaction/R01070"
  vG3PDH hypernym "http://identifiers.org/ec-code/1.1.1.8"
  vGAPDH homolog "http://identifiers.org/reactome/REACT_1847"
  vGAPDH identity "http://identifiers.org/ec-code/1.2.1.12",
                  "http://identifiers.org/kegg.reaction/R01061"
  vPGK homolog "http://identifiers.org/reactome/REACT_1771"
  vPGK identity "http://identifiers.org/ec-code/2.7.2.3",
                "http://identifiers.org/kegg.reaction/R01512"
  vPGM homolog "http://identifiers.org/reactome/REACT_576"
  vPGM identity "http://identifiers.org/ec-code/5.4.2.1",
                "http://identifiers.org/kegg.reaction/R01518"
  vENO homolog "http://identifiers.org/reactome/REACT_1400"
  vENO identity "http://identifiers.org/ec-code/4.2.1.11",
                "http://identifiers.org/kegg.reaction/R00658"
  vPYK homolog "http://identifiers.org/reactome/REACT_1911"
  vPYK identity "http://identifiers.org/ec-code/2.7.1.40",
                "http://identifiers.org/kegg.reaction/R00200"
  vPDC identity "http://identifiers.org/ec-code/4.1.1.1",
                "http://identifiers.org/kegg.reaction/R00224"
  vSUC hypernym "http://identifiers.org/go/GO:0006105"
  vADH homolog "http://identifiers.org/reactome/REACT_799"
  vADH hypernym "http://identifiers.org/ec-code/1.1.1.2",
                "http://identifiers.org/kegg.reaction/R00746"
  vATP hypernym "http://identifiers.org/ec-code/3.6.1.3",
                "http://identifiers.org/go/GO:0016887"
  vTPI hypernym "http://identifiers.org/kegg.reaction/R01015"
  vTPI hypernym "http://identifiers.org/go/GO:0004807"
  vTPI hypernym "http://identifiers.org/ec-code/5.3.1.1"
  vG6PDH hypernym "http://identifiers.org/kegg.reaction/R00835"
  vG6PDH hypernym "http://identifiers.org/ec-code/1.1.1.49"
  vG6PDH hypernym "http://identifiers.org/go/GO:0004345"
  v6PGL hypernym "http://identifiers.org/go/GO:0017057"
  v6PGL hypernym "http://identifiers.org/kegg.reaction/R02035"
  vGluDH hypernym "http://identifiers.org/kegg.reaction/R01528"
  vGluDH hypernym "http://identifiers.org/go/GO:0004616"
  vPPI hypernym "http://identifiers.org/kegg.reaction/R01056"
  vPPI hypernym "http://identifiers.org/go/GO:0004751"
  vTransk1 hypernym "http://identifiers.org/go/GO:0004802"
  vTransk1 hypernym "http://identifiers.org/kegg.reaction/R01641"
  vTransald hypernym "http://identifiers.org/go/GO:0004801"
  vTransald hypernym "http://identifiers.org/kegg.reaction/R01827"
  vTransk2 hypernym "http://identifiers.org/kegg.reaction/R01830"
  vTransk2 hypernym "http://identifiers.org/go/GO:0004802"
  vNADPH hypernym "http://identifiers.org/go/GO:0070995"
  vGLT hypernym "http://identifiers.org/go/GO:0046323"
  vGLT homolog "http://identifiers.org/reactome/REACT_2092"
end

ralser is "Ralser2007_Carbohydrate_Rerouting_ROS"

ralser model_entity_is "http://identifiers.org/biomodels.db/MODEL1003300000"
ralser model_entity_is "http://identifiers.org/biomodels.db/BIOMD0000000247"
ralser description "http://identifiers.org/pubmed/18154684"
ralser origin "http://identifiers.org/biomodels.db/BIOMD0000000064"
ralser version "http://identifiers.org/kegg.pathway/sce00030",
               "http://identifiers.org/kegg.pathway/sce00010"
ralser version "http://identifiers.org/go/GO:0006098",
               "http://identifiers.org/go/GO:0006096",
               "http://identifiers.org/go/GO:0006739"
ralser hypernym "http://identifiers.org/go/GO:0034599"
ralser taxon "http://identifiers.org/taxonomy/4932"
