// Created by libAntimony v2.13.0
model *MODEL7957942740()

  // Compartments and Species:
  compartment compartment_;
  species $OCT4_Gene in compartment_, $NANOG_Gene in compartment_, $SOX2_Gene in compartment_;
  species $targetGene in compartment_, $degradation in compartment_, $p53 in compartment_;
  species $A in compartment_, OCT4 in compartment_, SOX2 in compartment_;
  species NANOG in compartment_, OCT4_SOX2 in compartment_, Protein in compartment_;

  // Reactions:
  J0: $OCT4_Gene => OCT4; (eta1 + a1*A + a2*OCT4_SOX2 + a3*OCT4_SOX2*NANOG)/(1 + eta1/f + b1*A + b2*OCT4_SOX2 + b3*OCT4_SOX2*NANOG);
  J1: OCT4 => $degradation; gamma1*OCT4;
  J2: $NANOG_Gene => NANOG; (eta5 + e1*OCT4_SOX2 + e2*OCT4_SOX2*NANOG)/(1 + eta5/f + f2*OCT4_SOX2 + f1*OCT4_SOX2*NANOG + f3*p53);
  J3: NANOG => $degradation; gamma2*NANOG;
  J4: OCT4 + SOX2 => OCT4_SOX2; k1c*OCT4*SOX2 - k2c*OCT4_SOX2;
  J5: OCT4_SOX2 => $degradation; k3c*OCT4_SOX2;
  J6: $SOX2_Gene => SOX2; (eta3 + c1*A + c2*OCT4_SOX2 + c3*OCT4_SOX2*NANOG)/(1 + eta3/f + d1*A + d2*OCT4_SOX2 + d3*OCT4_SOX2*NANOG);
  J7: SOX2 => $degradation; gamma3*SOX2;
  J8: $targetGene => Protein; (g1*OCT4_SOX2 + eta7)/(1 + eta7/f2 + h1*OCT4_SOX2 + h2*OCT4_SOX2*NANOG);
  J9: Protein => $degradation; gamma4*Protein;

  // Species initializations:
  OCT4_Gene = 0;
  NANOG_Gene = 0;
  SOX2_Gene = 0;
  targetGene = 0.01;
  degradation = 0;
  p53 = 0;
  A = 10;
  OCT4 = 0.01;
  SOX2 = 0.01;
  NANOG = 0.01;
  OCT4_SOX2 = 0.1;
  Protein = 0;

  // Compartment initializations:
  compartment_ = 1;

  // Variable initializations:
  eta1 = 0.0001;
  a1 = 1;
  a2 = 0.01;
  a3 = 0.5;
  f = 1000;
  b1 = 0.0011;
  b2 = 0.001;
  b3 = 0.001;
  gamma1 = 1;
  eta5 = 0.0001;
  e1 = 0.01;
  e2 = 0.1;
  f2 = 0.001;
  f1 = 0.001;
  f3 = 0.05;
  gamma2 = 1;
  k1c = 0.05;
  k2c = 0.001;
  k3c = 5;
  eta3 = 0.0001;
  c1 = 1;
  c2 = 0.01;
  c3 = 0.5;
  d1 = 0.0011;
  d2 = 0.001;
  d3 = 0.001;
  gamma3 = 1;
  g1 = 0.1;
  eta7 = 0.0001;
  h1 = 0.0011;
  h2 = 1;
  gamma4 = 0.01;

  // Other declarations:
  const compartment_, eta1, a1, a2, a3, f, b1, b2, b3, gamma1, eta5, e1, e2;
  const f2, f1, f3, gamma2, k1c, k2c, k3c, eta3, c1, c2, c3, d1, d2, d3, gamma3;
  const g1, eta7, h1, h2, gamma4;

  // Unit definitions:
  unit substance = dimensionless;
  unit Volume = dimensionless;
  unit Time = dimensionless;

  // Display Names:
  substance is "arb_substance";
  Volume is "arb_volume";
  Time is "arb_time";

  // CV terms:
  compartment_ hypernym "http://identifiers.org/obo.go/GO:0005623"
  OCT4_Gene hypernym "http://identifiers.org/ensembl/ENSG00000204531"
  OCT4_Gene encodement "http://identifiers.org/uniprot/Q01860"
  NANOG_Gene encodement "http://identifiers.org/uniprot/Q8N7R0"
  NANOG_Gene hypernym "http://identifiers.org/ensembl/ENSG00000176654"
  SOX2_Gene hypernym "http://identifiers.org/ensembl/ENSG00000165661"
  SOX2_Gene encodement "http://identifiers.org/uniprot/Q6ZRP7"
  p53 hypernym "http://identifiers.org/uniprot/P04637"
  OCT4 hypernym "http://identifiers.org/uniprot/Q01860"
  SOX2 hypernym "http://identifiers.org/uniprot/Q6ZRP7"
  NANOG hypernym "http://identifiers.org/uniprot/Q8N7R0"
  OCT4_SOX2 part "http://identifiers.org/uniprot/Q01860",
                 "http://identifiers.org/uniprot/Q6ZRP7"
  J0 hypernym "http://identifiers.org/obo.go/GO:0010467"
  J1 hypernym "http://identifiers.org/obo.go/GO:0030163"
  J2 hypernym "http://identifiers.org/obo.go/GO:0010467"
  J3 hypernym "http://identifiers.org/obo.go/GO:0030163"
  J4 hypernym "http://identifiers.org/obo.go/GO:0006461"
  J5 hypernym "http://identifiers.org/obo.go/GO:0030163"
  J6 hypernym "http://identifiers.org/obo.go/GO:0010467"
  J7 hypernym "http://identifiers.org/obo.go/GO:0030163"
  J8 hypernym "http://identifiers.org/obo.go/GO:0010467"
  J9 hypernym "http://identifiers.org/obo.go/GO:0030163"
end

MODEL7957942740 is "Chickarmane2006 - Stem cell switch irreversible"

MODEL7957942740 model_entity_is "http://identifiers.org/biomodels.db/MODEL7957942740"
MODEL7957942740 model_entity_is "http://identifiers.org/biomodels.db/BIOMD0000000204"
MODEL7957942740 description "http://identifiers.org/pubmed/16978048"
MODEL7957942740 taxon "http://identifiers.org/taxonomy/9606",
                      "http://identifiers.org/taxonomy/10090"
MODEL7957942740 hypernym "http://identifiers.org/obo.go/GO:0048863"
