// Created by libAntimony v2.13.0
model *Hornberg2005_ERKcascade()

  // Compartments and Species:
  compartment compartment_;
  substanceOnly species R in compartment_, Rin in compartment_, x1 in compartment_;
  substanceOnly species x1p in compartment_, x2 in compartment_, x2p in compartment_;
  substanceOnly species x3 in compartment_, x3p in compartment_;

  // Reactions:
  v1: R -> Rin; v1_Vm1*R/(v1_Km1 + R);
  v2: Rin -> R; v2_Vm2*Rin/(v2_Km2 + Rin);
  v3: x1 -> x1p; v3_k3*R*x1/(v3_Km3 + x1);
  v4: x1p -> x1; v4_Vm4*x1p/(v4_Km4 + x1p);
  v5: x2 -> x2p; v5_k5*x1p*x2/(v5_Km5 + x2);
  v6: x2p -> x2; v6_Vm6*x2p/(v6_Km6 + x2p);
  v7: x3 -> x3p; v7_k7*x2p*x3/(v7_Km7 + x3);
  v8: x3p -> x3; v8_Vm8*x3p/v8_Km8/(1 + x3p/v8_Km8 + v8_Inh/v8_Ki8);

  // Species initializations:
  R = 0.5/compartment_;
  Rin = 0;
  x1 = 1/compartment_;
  x1p = 0;
  x2 = 1/compartment_;
  x2p = 0;
  x3 = 1/compartment_;
  x3p = 0;

  // Compartment initializations:
  compartment_ = 1;

  // Variable initializations:
  v1_Vm1 = 1;
  v1_Km1 = 0.1;
  v2_Vm2 = 0.01;
  v2_Km2 = 0.1;
  v3_k3 = 1;
  v3_Km3 = 0.1;
  v4_Vm4 = 0.3;
  v4_Km4 = 1;
  v5_k5 = 1;
  v5_Km5 = 0.1;
  v6_Vm6 = 0.3;
  v6_Km6 = 1;
  v7_k7 = 1;
  v7_Km7 = 0.1;
  v8_Vm8 = 0.3;
  v8_Km8 = 1;
  v8_Inh = 0;
  v8_Ki8 = 1;

  // Other declarations:
  const compartment_;

  // Unit definitions:
  unit substance = item;

  // Display Names:
  substance is "dimensionless";
  compartment_ is "Cytosol";
  v1 is "Receptor inactivation";
  v2 is "Receptor activation";
  v3 is "Kinase-1 activation";
  v4 is "Kinase-1 inactivation";
  v5 is "Kinase-2 activation";
  v6 is "Kinase-2 inactivation";
  v7 is "Kinase-3 activation";
  v8 is "Kinase-3 inactivation";

  // CV terms:
  compartment_ identity "http://identifiers.org/obo.go/GO:0005829"
  R hypernym "http://identifiers.org/uniprot/Q9QX70"
  Rin hypernym "http://identifiers.org/uniprot/Q9QX70"
  x1 hypernym "http://identifiers.org/uniprot/P04049"
  x1p hypernym "http://identifiers.org/uniprot/P04049"
  x2 hypernym "http://identifiers.org/uniprot/Q02750"
  x2p hypernym "http://identifiers.org/uniprot/Q02750"
  x3 hypernym "http://identifiers.org/uniprot/P28482"
  x3p hypernym "http://identifiers.org/uniprot/P28482"
  v1 hypernym "http://identifiers.org/obo.go/GO:0007175"
  v2 hypernym "http://identifiers.org/obo.go/GO:0045741"
  v3 identity "http://identifiers.org/obo.go/GO:0000185"
  v4 identity "http://identifiers.org/obo.go/GO:0051390"
  v5 identity "http://identifiers.org/ec-code/2.7.11.1",
              "http://identifiers.org/obo.go/GO:0000186",
              "http://identifiers.org/obo.go/GO:0004709"
  v6 identity "http://identifiers.org/obo.go/GO:0051389"
  v7 identity "http://identifiers.org/ec-code/2.7.12.2",
              "http://identifiers.org/obo.go/GO:0000187",
              "http://identifiers.org/obo.go/GO:0004708"
  v8 hypernym "http://identifiers.org/obo.go/GO:0043407"
end

Hornberg2005_ERKcascade is "Hornberg2005_ERKcascade"

Hornberg2005_ERKcascade model_entity_is "http://identifiers.org/biomodels.db/MODEL6623610941"
Hornberg2005_ERKcascade model_entity_is "http://identifiers.org/biomodels.db/BIOMD0000000084"
Hornberg2005_ERKcascade description "http://identifiers.org/pubmed/15634347"
Hornberg2005_ERKcascade identity "http://identifiers.org/obo.go/GO:0000165",
                                 "http://identifiers.org/obo.go/GO:0007173"
Hornberg2005_ERKcascade part "http://identifiers.org/kegg.pathway/rno04010"
Hornberg2005_ERKcascade taxon "http://identifiers.org/taxonomy/40674"
