// Created by libAntimony v2.13.0
model *Markevich2004_MAPK_orderedMM()

  // Compartments and Species:
  compartment uVol;
  species M in uVol, Mp in uVol, Mpp in uVol, $MAPKK in uVol, $MKP3 in uVol;

  // Reactions:
  v1: M => Mp; uVol*(k1cat*MAPKK*M/Km1/(1 + M/Km1 + Mp/Km2));
  v2: Mp => Mpp; uVol*(k2cat*MAPKK*Mp/Km2/(1 + M/Km1 + Mp/Km2));
  v3: Mpp => Mp; uVol*(k3cat*MKP3*Mpp/Km3/(1 + Mpp/Km3 + Mp/Km4 + M/Km5));
  v4: Mp => M; uVol*(k4cat*MKP3*Mp/Km4/(1 + Mpp/Km3 + Mp/Km4 + M/Km5));

  // Species initializations:
  M = 500/uVol;
  Mp = 0;
  Mpp = 0;
  MAPKK = 50/uVol;
  MKP3 = 100/uVol;

  // Compartment initializations:
  uVol = 1;

  // Variable initializations:
  k1cat = 0.01;
  Km1 = 50;
  k2cat = 15;
  Km2 = 500;
  k3cat = 0.084;
  Km3 = 22;
  k4cat = 0.06;
  Km4 = 18;
  Km5 = 78;

  // Other declarations:
  const uVol, k1cat, Km1, k2cat, Km2, k3cat, Km3, k4cat, Km4, Km5;

  // Unit definitions:
  unit substance = 1e-9 mole;

  // Display Names:
  substance is "nanomole (default)";
  v1 is "phosphorylation of MAPK";
  v2 is "phosphorylation of P-MAPK";
  v3 is "dephosphorylation of PP-MAPK";
  v4 is "dephosphorylation of P-MAPK";

  // CV terms:
  M hypernym "http://identifiers.org/uniprot/P26696"
  Mp hypernym "http://identifiers.org/uniprot/P26696"
  Mpp hypernym "http://identifiers.org/uniprot/P26696"
  MAPKK identity "http://identifiers.org/uniprot/Q05116"
  MKP3 identity "http://identifiers.org/uniprot/Q90W58"
  v1 homolog "http://identifiers.org/reactome/REACT_2247",
             "http://identifiers.org/reactome/REACT_136"
  v1 hypernym "http://identifiers.org/ec-code/2.7.12.2",
              "http://identifiers.org/go/GO:0004708",
              "http://identifiers.org/go/GO:0006468"
  v2 homolog "http://identifiers.org/reactome/REACT_136",
             "http://identifiers.org/reactome/REACT_2247"
  v2 hypernym "http://identifiers.org/ec-code/2.7.12.2",
              "http://identifiers.org/go/GO:0004708",
              "http://identifiers.org/go/GO:0000187",
              "http://identifiers.org/go/GO:0006468"
  v3 hypernym "http://identifiers.org/ec-code/3.1.3.16",
              "http://identifiers.org/go/GO:0000188",
              "http://identifiers.org/go/GO:0006470"
  v4 hypernym "http://identifiers.org/ec-code/3.1.3.16",
              "http://identifiers.org/go/GO:0006470"
end

Markevich2004_MAPK_orderedMM is "Markevich2004 - MAPK double phosphorylation,  ordered Michaelis-Menton"

Markevich2004_MAPK_orderedMM model_entity_is "http://identifiers.org/biomodels.db/MODEL6618496308"
Markevich2004_MAPK_orderedMM model_entity_is "http://identifiers.org/biomodels.db/BIOMD0000000027"
Markevich2004_MAPK_orderedMM description "http://identifiers.org/pubmed/14744999"
Markevich2004_MAPK_orderedMM hypernym "http://identifiers.org/go/GO:0000165"
Markevich2004_MAPK_orderedMM taxon "http://identifiers.org/taxonomy/8355"
