// Created by libAntimony v2.13.0
model *BIOMD0000000005()

  // Compartments and Species:
  compartment cell;
  species $EmptySet in cell, C2 in cell, CP in cell, M in cell, pM in cell;
  species Y in cell, YP in cell, $YT in cell, $CT in cell;

  // Assignment Rules:
  YT := Y + YP + M + pM;
  CT := C2 + CP + M + pM;

  // Reactions:
  Reaction1: M => C2 + YP; cell*Reaction1_k6*M;
  Reaction2: C2 => CP; cell*C2*Reaction2_k8notP;
  Reaction3: CP => C2; cell*CP*Reaction3_k9;
  Reaction4: CP + Y => pM; cell*CP*Reaction4_k3*Y;
  Reaction5: M => pM; cell*Reaction5_k5notP*M;
  Reaction6: $EmptySet => Y; cell*Reaction6_k1aa;
  Reaction7: Y => $EmptySet; cell*Reaction7_k2*Y;
  Reaction8: YP => $EmptySet; cell*Reaction8_k7*YP;
  Reaction9: pM => M; cell*pM*(Reaction9_k4prime + Reaction9_k4*(M/CT)^2);

  // Species initializations:
  EmptySet = 0;
  C2 = 0;
  CP = 0.75/cell;
  M = 0;
  pM = 0.25/cell;
  Y = 0;
  YP = 0;

  // Compartment initializations:
  cell = 1;

  // Variable initializations:
  Reaction1_k6 = 1;
  Reaction2_k8notP = 1000000;
  Reaction3_k9 = 1000;
  Reaction4_k3 = 200;
  Reaction5_k5notP = 0;
  Reaction6_k1aa = 0.015;
  Reaction7_k2 = 0;
  Reaction8_k7 = 0.6;
  Reaction9_k4 = 180;
  Reaction9_k4prime = 0.018;

  // Other declarations:
  const cell;

  // Display Names:
  C2 is "cdc2k";
  CP is "cdc2k-P";
  M is "p-cyclin_cdc2";
  pM is "p-cyclin_cdc2-p";
  Y is "cyclin";
  YP is "p-cyclin";
  YT is "total_cyclin";
  CT is "total_cdc2";
  Reaction1 is "cyclin_cdc2k dissociation";
  Reaction2 is "cdc2k phosphorylation";
  Reaction3 is "cdc2k dephosphorylation";
  Reaction4 is "cyclin cdc2k-p association";
  Reaction5 is "deactivation of cdc2 kinase";
  Reaction6 is "cyclin biosynthesis";
  Reaction7 is "default degradation of cyclin";
  Reaction8 is "cdc2 kinase triggered degration of cyclin";
  Reaction9 is "activation of cdc2 kinase";

  // CV terms:
  cell identity "http://identifiers.org/obo.go/GO:0005623"
  C2 hypernym "http://identifiers.org/uniprot/P04551"
  CP hypernym "http://identifiers.org/uniprot/P04551"
  M part "http://identifiers.org/uniprot/P04551",
         "http://identifiers.org/interpro/IPR006670"
  pM part "http://identifiers.org/uniprot/P04551",
          "http://identifiers.org/interpro/IPR006670"
  Y hypernym "http://identifiers.org/interpro/IPR006670"
  YP hypernym "http://identifiers.org/interpro/IPR006670"
  YT hypernym "http://identifiers.org/interpro/IPR006670"
  CT hypernym "http://identifiers.org/uniprot/P04551"
  Reaction1 version "http://identifiers.org/reactome/REACT_6308"
  Reaction1 hypernym "http://identifiers.org/obo.go/GO:0000079"
  Reaction2 hypernym "http://identifiers.org/ec-code/2.7.11.1",
                     "http://identifiers.org/obo.go/GO:0006468"
  Reaction3 hypernym "http://identifiers.org/ec-code/3.1.3.16",
                     "http://identifiers.org/obo.go/GO:0006470"
  Reaction4 version "http://identifiers.org/reactome/REACT_6216",
                    "http://identifiers.org/reactome/REACT_6308"
  Reaction5 hypernym "http://identifiers.org/ec-code/2.7.10.2",
                     "http://identifiers.org/obo.go/GO:0006468",
                     "http://identifiers.org/obo.go/GO:0045736"
  Reaction5 version "http://identifiers.org/reactome/REACT_3178",
                    "http://identifiers.org/reactome/REACT_6327"
  Reaction6 hypernym "http://identifiers.org/obo.go/GO:0006412"
  Reaction7 hypernym "http://identifiers.org/obo.go/GO:0008054"
  Reaction8 hypernym "http://identifiers.org/obo.go/GO:0008054"
  Reaction9 version "http://identifiers.org/reactome/REACT_6257",
                    "http://identifiers.org/reactome/REACT_6175",
                    "http://identifiers.org/reactome/REACT_6294"
  Reaction9 hypernym "http://identifiers.org/ec-code/3.1.3.16",
                     "http://identifiers.org/obo.go/GO:0006470",
                     "http://identifiers.org/obo.go/GO:0045737"
end

BIOMD0000000005 is "Tyson1991 - Cell Cycle 6 var"

BIOMD0000000005 model_entity_is "http://identifiers.org/biomodels.db/MODEL6614644188"
BIOMD0000000005 model_entity_is "http://identifiers.org/biomodels.db/BIOMD0000000005"
BIOMD0000000005 description "http://identifiers.org/pubmed/1831270"
BIOMD0000000005 taxon "http://identifiers.org/taxonomy/33154"
BIOMD0000000005 hypernym "http://identifiers.org/kegg.pathway/sce04111",
                         "http://identifiers.org/obo.go/GO:0000278"
BIOMD0000000005 version "http://identifiers.org/reactome/REACT_152"
