A study reports that the gene {gene} is associated with this trait:

    "{phenotype}"

Below are traits that a public database already links to {gene}. They are the ones closest in meaning to the reported trait, drawn from a longer list.

For each numbered entry, say how it relates to the reported trait, using exactly one of these eleven tags.

EXACT
    The same trait as the reported one, under any wording, abbreviation, synonym
    or spelling, or a trivially different way of measuring the same quantity.

PARENT_FIRST
    The immediate parent: the reported trait is directly one of its stages,
    grades, subtypes or forms, with no intervening category.

PARENT_DISTANT
    A parent further up: it still covers the reported trait, but only through one
    or more intervening categories, and it covers a great many other conditions
    besides.

CHILD_FIRST
    The immediate child: directly one of the reported trait's stages, grades,
    subtypes or named forms, or a component the reported trait directly
    aggregates or is directly derived from.

CHILD_DISTANT
    A child further down: inside the reported trait, but a subtype of a subtype,
    or a component of a component.

CLOSE_VERY
    Not the same trait, but so tightly linked in the population that a genetic
    signal on one would almost certainly appear on the other, as with two
    measurements of the same underlying quantity.

CLOSE_MODERATE
    Linked firmly enough that a genetic signal on one would often appear on the
    other, but not dependably.

CLOSE_VAGUE
    Some shared biology or resemblance, but no reliable expectation that a
    genetic signal on one would appear on the other.

SYMPTOM_SPECIFIC
    The reported trait is a defining or near-constant feature of this entry, or
    the measurement by which this entry is diagnosed, and few other conditions
    produce it in the same way. May also be read in reverse, the entry being a
    defining feature of the reported trait.

SYMPTOM_MODERATE
    This entry commonly produces the reported trait, or the reverse, but so do
    many other conditions.

SYMPTOM_NONSPECIFIC
    The link exists only through a marker that a very large number of conditions
    produce, such as a general inflammatory or biochemical derangement, or it
    runs through a third condition rather than between these two directly.

DIFFERENT
    The tie is no stronger than belonging to the same broad field, organ,
    category or class of disease. Two distinct conditions that merely sit under
    a common heading are DIFFERENT: LDL cholesterol and HDL cholesterol are both
    lipid measurements yet are largely uncorrelated, so each is DIFFERENT from
    the other. Judge the strength of the biological tie, not the similarity of
    the words.

Judge every entry on its own. Do not decide an overall verdict, and do not rank
the entries against each other.

Reply with one line per entry and nothing else, in exactly this format:

    <number> | <TAG> | <reason, at most twelve words>

Traits already linked to {gene}:

{traits}
