| Description: |
This model neuron implements a slightly modified version of the
neuron model described in [1]. The most important properties are:
- Integrate-and-fire with threshold that is increased on spiking
and decays back to an equilibrium value.
- No hard reset, but repolarizing potassium current.
- AMPA, NMDA, GABA_A, and GABA_B conductance-based synapses with
beta-function (difference of two exponentials) time course.
- Intrinsic currents I_h (pacemaker), I_T (low-threshold calcium),
I_Na(p) (persistent sodium), and I_KNa (depolarization-activated
potassium).
In comparison to the model described in the paper, the following
modifications were mare:
- NMDA conductance is given by g(t) = g_peak * m(V), where
m(V) = 1 / ( 1 + exp( - ( V - NMDA_Vact ) / NMDA_Sact ) )
This is an approximation to the NMDA model used in [2].
- Several apparent typographical errors in the descriptions of
the intrinsic currents were fixed, hopefully in a meaningful
way.
I'd like to thank Sean Hill for giving me access to his
simulator source code.
See examples/hilltononi for usage examples.
Warning:
THIS MODEL NEURON HAS NOT BEEN TESTED EXTENSIVELY!
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| Parameters: |
V_m - membrane potential
spike_duration - duration of re-polarizing potassium current
Tau_m - membrane time constant applying to all currents but repolarizing K-current
(see [1, p 1677])
Tau_spike - membrane time constant applying to repolarizing K-current
Theta, Theta_eq, Tau_theta - Threshold, equilibrium value, time constant
g_KL, E_K, g_NaL, E_Na - conductances and reversal potentials for K and Na leak currents
{AMPA,NMDA,GABA_A,GABA_B}_{E_rev,g_peak,Tau_1,Tau_2}
- reversal potentials, peak conductances and time constants for synapses
(Tau_1: rise time, Tau_2: decay time, Tau_1 < Tau_2)
NMDA_Sact, NMDA_Vact - Parameters for voltage dependence of NMDA-synapse, see eq. above
{h,T,NaP,KNa}_{E_rev,g_peak} - reversal potential and peak conductance for intrinsic currents
receptor_types - dictionary mapping synapse names to ports on neuron model
recordables - list of recordable quantities.
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