\usepackage {colortbl}
\begin{tabular}{lrr}
  \large\textbf{Table title}\\[2mm]
  \textbf{Description}
           & \textbf{Column 1}
              & \textbf{Column 2}\\[1mm]
  Row one  & mmmmmm & mmmmm  \\
  Row two  &  mmmmm & mmmm   \\
  Row three& mmmmmm & mmmmmm \\
  Row four & mmmmmm & mmmmm  \\
\cline{2-3}
  Totals   & mmmmmm & mmmmmm
\end{tabular}
